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PCDHGB2 Produkte

(Protocadherin gamma Subfamily B, 2 (PCDHGB2))
This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008].

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Ausgewählte PCDHGB2 Kategorien

PCDHGB2 Antikörper

High quality antibodies with extensive validation data.

PCDHGB2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PCDHGB2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (3)
Kat. Nr. ABIN565980
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN1539095
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
Kat. Nr. ABIN565979
Menge 50 μL
Datenblatt Datenblatt

Empfohlene PCDHGB2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1314264
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1314266
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2728396
Menge 20 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PCDHGB2 Produkten

Lobas, Helsper, Vernon, Schreiner, Zhang, Holtzman, Thedens, Weiner: "Molecular heterogeneity in the choroid plexus epithelium: the 22-member ?-protocadherin family is differentially expressed, apically localized, and implicated in CSF regulation." in: Journal of neurochemistry, Vol. 120, Issue 6, pp. 913-27, (2012) (PubMed).

Prasad, Weiner: "Direct and Indirect Regulation of Spinal Cord Ia Afferent Terminal Formation by the ?-Protocadherins." in: Frontiers in molecular neuroscience, Vol. 4, pp. 54, (2012) (PubMed).

Synonyme und alternative Namen zu PCDHGB2

protocadherin gamma subfamily B, 2 (PCDHGB2), protocadherin gamma subfamily B, 2 (Pcdhgb2), PCDH-GAMMA-B2

Bezeichner auf Proteinebene für PCDHGB2

  • protocadherin gamma-B2
  • 3' RACE product
  • protocadherin gamma B2
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