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IL-36beta (human) Matched Pair Detection Set

ELISA Reaktivität: Human ELISA unconjugated Wirt: Maus, Kaninchen
Produktnummer ABIN6253509
  • Target Alle FIL1h Produkte
    FIL1h (Interleukin 1 eta (FIL1h))
    Reaktivität
    Human
    Nachweismethode
    Colorimetric
    Wirt
    Maus, Kaninchen
    Methodentyp
    Sandwich ELISA
    Detektionsbereich
    15.6 pg/mL - 1000 pg/mL
    Untere Nachweisgrenze
    15.6 pg/mL
    Applikation
    ELISA
    Verwendungszweck
    IL-36beta (human) Matched Pair Detection Set
    Sensitivität
    10 pg/mL
    Produktmerkmale
    Matched Pair Detection Set. Detects human IL-36beta in cell culture supernatant. Colorimetric assay. Sample Type: Cell Culture Supernatant. Range: 15.6 to 1000 pg/mL. Sensitivity: 10 pg/mL. IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
    Bestandteile
    1 vial standard protein (100ng) (lyophilized) [STD] 1 vial coating antibody (270μl) [COAT] 1 vial detection antibody (60μl) [DET] 1 vial streptavidin-HRP (10μg) (lyophilized) [STREP]
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    Lot specific
    Handhabung
    Avoid freeze/thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung

    Short Term Storage: -20°C

    Long Term Storage: -20°C

    Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.

  • Target
    FIL1h (Interleukin 1 eta (FIL1h))
    Andere Bezeichnung
    IL-36beta (FIL1h Produkte)
    Synonyme
    2310043N20Rik Matched Antibody Pair, Il36b Matched Antibody Pair, FIL1 Matched Antibody Pair, FIL1-(ETA) Matched Antibody Pair, FIL1H Matched Antibody Pair, FILI-(ETA) Matched Antibody Pair, IL-1F8 Matched Antibody Pair, IL-1H2 Matched Antibody Pair, IL1-ETA Matched Antibody Pair, IL1F8 Matched Antibody Pair, IL1H2 Matched Antibody Pair, Il1f8 Matched Antibody Pair, interleukin 1 family, member 8 Matched Antibody Pair, interleukin 36 beta Matched Antibody Pair, interleukin 36, beta Matched Antibody Pair, Il1f8 Matched Antibody Pair, IL36B Matched Antibody Pair, Il36b Matched Antibody Pair
    Hintergrund

    Alternate Names/Synonyms: Interleukin-36beta Interleukin-1 Family Member 8, IL-1F8

    Product Description: IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.

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