IL-36beta (human) Matched Pair Detection Set
Kurzübersicht für IL-36beta (human) Matched Pair Detection Set (ABIN6253509)
Target
Reaktivität
Wirt
Applikation
-
-
Nachweismethode
- Colorimetric
-
Methodentyp
- Sandwich ELISA
-
Detektionsbereich
- 15.6 pg/mL - 1000 pg/mL
-
Untere Nachweisgrenze
- 15.6 pg/mL
-
Verwendungszweck
- IL-36beta (human) Matched Pair Detection Set
-
Sensitivität
- 10 pg/mL
-
Produktmerkmale
- Matched Pair Detection Set. Detects human IL-36beta in cell culture supernatant. Colorimetric assay. Sample Type: Cell Culture Supernatant. Range: 15.6 to 1000 pg/mL. Sensitivity: 10 pg/mL. IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
-
Bestandteile
- 1 vial standard protein (100ng) (lyophilized) [STD] 1 vial coating antibody (270μl) [COAT] 1 vial detection antibody (60μl) [DET] 1 vial streptavidin-HRP (10μg) (lyophilized) [STREP]
-
-
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- Lot specific
-
Handhabung
- Avoid freeze/thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
-
Short Term Storage: -20°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 1 year after receipt when stored at -20°C.
-
-
- FIL1h (Interleukin 1 eta (FIL1h))
-
Andere Bezeichnung
- IL-36beta
-
Hintergrund
-
Alternate Names/Synonyms: Interleukin-36beta Interleukin-1 Family Member 8, IL-1F8
Product Description: IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
Target
-
