CD4 FITC - CD28 PE Bi-Test Reagent
FACS
Reaktivität: Human
FACS
FITC,PE
Wirt: Maus
Quick Overview for CD4 FITC - CD28 PE Bi-Test Reagent (ABIN2763724)
Target
CD4 + CD28
Reaktivität
Human
Wirt
Maus
Konjugat
FITC,PE
Applikation
Flow Cytometry (FACS)
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Marke
- Bi-Test™
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Aufreinigung
- Protein A/G Chromatography
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Isotyp
- IgG1
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- 4 °C
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- CD4 + CD28
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Andere Bezeichnung
- CD4, CD28
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Hintergrund
- Identification of CD4 on human helper/inducer T cells expressing the 60,000 M.W. surface antigen (HLA class II reactive). CD4 is present in low density on monocytes. Anti-human CD28 binds the 44 kDa MW cell surface protein on the surface of most T cells. CD28 acts as the ligand for the B7/BB-1 Molecule on the surface of activated B cells. B7/BB-1 co-stimulates T cells through CD28, along with CD2 and CD3. CD28 antigen is a disulfide-linked homodimeric glycoprotein. The CD28 antigen is present on approximately 60 % -80 % of lymphocytes (95 % of CD4 and 50 % of CD8 lymphocytes). CD28 regulates the expression of cytokines by T cells, not only IL-2, but also IL-1 alpha and CSF-1, usually synthesized by accessory cells. CD28 functions as a cell adhesion molecule (CAM) for certain T cell subsets.
Target
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