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PPM1D Proteine

6 Treffer:

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 1-605) protein (His tag) Protein

Crystallography grade PPM1D Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Produktnummer ABIN3086448
$10,832.86
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
1 mg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 60 Werktagen

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 1-598) protein (His tag) Protein

Crystallography grade PPM1D Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Produktnummer ABIN3130585
$10,832.86
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
1 mg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 60 Werktagen

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 98-375) protein (His tag) Protein

PPM1D Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
Produktnummer ABIN5623952
$575.18
Zzgl. Versandkosten $45.00
50 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 9 bis 11 Werktagen

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 1-605) protein (GST tag) Protein

PPM1D Spezies: Human Wirt: Wheat germ Recombinant AP, AA, ELISA, WB
Produktnummer ABIN1315909
$498.33
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
2 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 12 Werktagen

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) (AA 496-605) protein (GST tag) Protein

PPM1D Spezies: Human Wirt: Wheat germ Recombinant AP, AA, ELISA, WB
Produktnummer ABIN1315910
$574.29
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
10 μg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 12 Werktagen

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D) protein (Myc-DYKDDDDK Tag) Protein

PPM1D Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
Produktnummer ABIN2729806
$971.30
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
20 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 Werktagen
  • Typ Protein
    • Protein
  • Target Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D)
    • Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D)
    • Hemagglutinin (HA)
    • Hemoglobin beta (HBB)
    • Ribosome Binding Factor A (RBFA)
    • Triosephosphate Isomerase 1 (TPI1)
    • S-Adenosyl-Methionine Synthase (METK)
    • Hemoglobin, alpha 1 (HBA1)
    • SARS-CoV-2 Spike
    • Myoglobin (MB)
    • Tumor Necrosis Factor alpha (TNF alpha)
    • Thymidylate Kinase (Tmk)
    • Lipoyl synthase (lipA)
    • Growth Hormone 1 (GH1)
    • Interferon gamma (IFNG)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • Aspartate Carbamoyltransferase (PYRB)
    • Uracil-DNA Glycosylase (UNG)
    • Malate Dehydrogenase (MDH)
    • Phosphoglucosamine Mutase (GLMM)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • phosphatidylserine Decarboxylase (PISD)
    • Cysteinyl-tRNA Synthetase 2, Mitochondrial (Putative) (CARS2)
    • tRNA Methyltransferase 5 (TRMT5)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Interleukin 6 (IL6)
    • Interleukin 2 (IL2)
    • Cytochrome C, Somatic (CYCS)
    • Interleukin 4 (IL4)
    • Epidermal Growth Factor Receptor (EGFR)
    • CD40 Ligand (CD40LG)
    • Gp120
    • Porphobilinogen Deaminase (HEMC)
    • Plasminogen Activator Inhibitor 1 (SERPINE1)
    • Superoxide Dismutase 1, Soluble (SOD1)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • 1-(5-Phosphoribosyl)-5-[(5-Phosphoribosylamino)methylideneamino] Imidazole-4-Carboxamide Isomerase (APG10)
    • Interleukin 10 (IL10)
    • Interleukin 8 (IL8)
    • Interleukin 1, beta (IL1B)
    • Prolactin (PRL)
    • Adenosylhomocysteinase (AHCY)
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Ferrochelatase, HEMH (HEMH)
    • Thymidylate Synthase (THYA)
    • Programmed Cell Death 1 (PDCD1)
    • SARS-CoV-2 Spike S1
    • Thymidine Kinase 1, Soluble (TK1)
    • Uracil Phosphoribosyltransferase (UPP)
    • beta-2-Microglobulin (B2M)
    • Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
    • Insulin-Like Growth Factor 1 (IGF1)
  • Anwendung
    • ELISA
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Crystallization (Crys)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Protein Interaction (PI)
    • Standard (STD)
  • Reaktivität
    • Human
    • Maus
  • Abbildungen verfügbar
  • Wirt
    • Insektenzellen
    • Wheat germ
    • Escherichia coli (E. coli)
    • HEK-293 Cells
  • Bindungsspezifität
    • AA 1-605
    • AA 1-598
    • AA 496-605
    • AA 98-375
  • Konjugat
    • Unkonjugiert
    • His tag
    • GST tag
    • Myc-DYKDDDDK Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Liquid
  • Grade
    • Crystallography grade

PPM1D Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. The expression of this gene is induced in a p53-dependent manner in response to various environmental stresses. While being induced by tumor suppressor protein TP53/p53, this phosphatase negatively regulates the activity of p38 MAP kinase, MAPK/p38, through which it reduces the phosphorylation of p53, and in turn suppresses p53-mediated transcription and apoptosis. This phosphatase thus mediates a feedback regulation of p38-p53 signaling that contributes to growth inhibition and the suppression of stress induced apoptosis. This gene is located in a chromosomal region known to be amplified in breast cancer. The amplification of this gene has been detected in both breast cancer cell line and primary breast tumors, which suggests a role of this gene in cancer development.

Alternative names and synonyms associated with PPM1D

  • protein phosphatase, Mg2+/Mn2+ dependent 1D (PPM1D) Antikörper
  • protein phosphatase 1D magnesium-dependent, delta isoform (Ppm1d) Antikörper
  • protein phosphatase, Mg2+/Mn2+ dependent, 1D (Ppm1d) Antikörper
  • protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog (ppm1d.L) Antikörper
  • protein phosphatase, Mg2+/Mn2+ dependent, 1Da (ppm1da) Antikörper
  • AV338790 Antikörper
  • PP2C-DELTA Antikörper
  • ppm1d Antikörper
  • Wip1 Antikörper
  • wu:fj44c08 Antikörper
  • zgc:55836 Antikörper
  • zgc:77316 Antikörper

Bezeichner auf Proteinebene für PPM1D

protein phosphatase 1D , protein phosphatase 1D magnesium-dependent, delta isoform , protein phosphatase 2C delta isoform , protein phosphatase Wip1 , wild-type p53-induced phosphatase 1 , PP2C-delta , p53-induced protein phosphatase 1 , protein phosphatase 2C isoform delta , protein phosphatase magnesium-dependent 1 delta , protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog , protein phosphatase, Mg2+/Mn2+ dependent, 1D , protein phosphatase 1D magnesium-dependent, delta

GENE ID SPEZIES
8493 Homo sapiens
53892 Mus musculus
287585 Rattus norvegicus
417644 Gallus gallus
514005 Bos taurus
612934 Canis lupus familiaris
100525714 Sus scrofa
443988 Xenopus laevis
394065 Danio rerio

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