anti-p300 (EP300) Antikörper

Bezeichnung:: anti-E1A Binding Protein P300 Antikörper (EP300)

Auf www.antikoerper-online.de finden Sie aktuell 289 E1A Binding Protein P300 (EP300) Antikörper von 21 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen p300 Kits (18) und p300 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 334 p300 Produkte verfügbar.

Synonyme:: A430090G16, A730011L11, KAT3B, p300, p300 HAT, RSTS2

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	EP300	2033	Q09472
	EP300	328572
	EP300	170915
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-p300 (EP300) Antikörper

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anti-Human p300 Antikörper:

anti-Mouse (Murine) p300 Antikörper:

anti-Rat (Rattus) p300 Antikörper:

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Am meisten referenzierte anti-p300 Antikörper

Human Monoclonal p300 Primary Antibody für ChIP, EM - ABIN152047 : Eckner, Ludlow, Lill, Oldread, Arany, Modjtahedi, DeCaprio, Livingston, Morgan: Association of p300 and CBP with simian virus 40 large T antigen. in Molecular and cellular biology 1996 (PubMed)
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Human Monoclonal p300 Primary Antibody für FACS, ICC - ABIN151948 : Eckner, Yao, Oldread, Livingston: Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. in Genes & development 1996 (PubMed)
Show all 5 Pubmed References
Human Polyclonal p300 Primary Antibody für DB - ABIN1881299 : Zhang, Zhang, Rui, Liu: p300-mediated acetylation stabilizes the Th-inducing POK factor. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
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Human Polyclonal p300 Primary Antibody für ChIP, ICC - ABIN152981 : Julien, Carriere, Moreau, Roux: mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling. in Molecular and cellular biology 2010 (PubMed)
Show all 4 Pubmed References
Human Monoclonal p300 Primary Antibody für ChIP, ICC - ABIN152048 : Eckner, Ewen, Newsome, Gerdes, DeCaprio, Lawrence, Livingston: Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. in Genes & development 1994 (PubMed)
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Human Monoclonal p300 Primary Antibody für ChIPSeq, ChIP - ABIN2668569 : Dallas, Yaciuk, Moran: Characterization of monoclonal antibodies raised against p300: both p300 and CBP are present in intracellular TBP complexes. in Journal of virology 1997 (PubMed)
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Human Monoclonal p300 Primary Antibody für ELISA, WB - ABIN969098 : Stauffer, Chang, Huang, Dunn, Thayer: p300/CREB-binding protein interacts with ATR and is required for the DNA replication checkpoint. in The Journal of biological chemistry 2007 (PubMed)
Show all 2 Pubmed References
Human Monoclonal p300 Primary Antibody für ELISA, WB - ABIN966068 : Geiger, Sharma, Kim, Nyborg: The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB. in Molecular and cellular biology 2008 (PubMed)
Show all 2 Pubmed References
Human Monoclonal p300 Primary Antibody für IF, IHC (p) - ABIN560748 : Wong, Pickard, McCance: p300 alters keratinocyte cell growth and differentiation through regulation of p21(Waf1/CIP1). in PLoS ONE 2010 (PubMed)
Human Polyclonal p300 Primary Antibody für DB, IHC (p) - ABIN389698 : Aubry, Shin, Crary, Lefort, Qureshi, Lefebvre, Califano, Shelanski: Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression. in PLoS ONE 2015 (PubMed)

Weitere Antikörper gegen p300 Interaktionspartner

Human E1A Binding Protein P300 (EP300) Interaktionspartner

High P300 expression is associated with recurrence in prostate cancer.
Data generated with primary human hepatic stellate cells (HSC) supports that stiffness-mediated HSC activation requires p300.
The histone acylation activity of p300 can be activated by pre-existing lysine crotonylation through a positive feedback mechanism.
epigenomic profiling of clear cell renal cell carcinoma (zeige MOK Antikörper) (ccRCC) establishes a compendium of somatically altered cis (zeige CISH Antikörper)-regulatory elements, uncovering new potential targets including ZNF395 (zeige ZNF395 Antikörper). Loss of VHL (zeige VHL Antikörper), a ccRCC signature event, causes pervasive enhancer malfunction, with binding of enhancer-centric HIF2a (zeige EPAS1 Antikörper) and recruitment of histone acetyltransferase p300 at preexisting lineage-specific promoter-enhancer complexes
Histone acetyltransferase (zeige HAT Antikörper) EP300 is necessary for the transcription factor SOX2 (zeige SOX2 Antikörper) activity in basal cells, including for induction of the squamous fate. EP300 copy number gains are common in squamous cell carcinoma SQCCs, including lung cancer SQCC cell lines.
High expression of EP300 is associated with colorectal cancer.
Transcriptional coactivator p300 gene polymorphism correlates with the development and advancement of diabetic kidney disease. Additionally, the SIRT1 (zeige SIRT1 Antikörper) gene collaborates with the p300 gene and participates in promoting albuminuria in type 2 diabetes mellitus patients.
These results reveal a novel RTK-AKT (zeige AKT1 Antikörper)-p300-ADA3 (zeige TADA3 Antikörper) signaling pathway involved in growth factor-induced cell cycle progression.
Study suggest that both p300 and CREB (zeige CREB1 Antikörper) are required for the function integrity of HIF-1alpha (zeige HIF1A Antikörper) transcription machinery and subsequent angiogenesis, suggesting future studies to improve burn wound healing might be directed to optimization of the interaction between p300, CREB (zeige CREB1 Antikörper) and HIF-1alpha (zeige HIF1A Antikörper).
These results suggest that EP300 harbors adaptive variants in Tibetans, which might contribute to high-altitude adaptation through regulating NO production.

Mouse (Murine) E1A Binding Protein P300 (EP300) Interaktionspartner

Study in mouse model found that liver stiffness activates hepatic stellate cells differentiation into myofibroblasts, which required nuclear accumulation of p300 (zeige NOTCH1 Antikörper).
Data (including data from studies in knockout and transgenic mice) suggest that Ep300 and Crebbp (zeige CREBBP Antikörper) are limiting cofactors for pancreatic islet development (including gene expression regulation and cell proliferation), and hence for postnatal glucose homeostasis, with some functional redundancy. (Ep300 = E1A binding protein p300; Crebbp (zeige CREBBP Antikörper) = CREB binding protein (zeige CREBBP Antikörper))
Here the authors report a lipopolysaccharide-induced NFkappaB enhanceosome in which TonEBP (zeige NFAT5 Antikörper) is required for the recruitment of p300 (zeige NOTCH1 Antikörper). Increased expression of TonEBP (zeige NFAT5 Antikörper) enhances the NFkappaB activity and reduced TonEBP (zeige NFAT5 Antikörper) expression lowers it.
Enhancer-priming by MLL3/MLL4 (zeige MLL4 Antikörper) followed by enhancer-activation by CBP/p300 (zeige CREBBP Antikörper) sequentially shape dynamic enhancer landscapes during cell differentiation
Data show that LPS (zeige TLR4 Antikörper) induces endoplasmic reticulum (ER) stress and P300 (zeige NOTCH1 Antikörper) activity via the XBP1 (zeige XBP1 Antikörper)/IRE1 (zeige ERN1 Antikörper) pathway.
Loss of p300 (zeige NOTCH1 Antikörper) expression is associated with leukemogenesis.
UTX (zeige KDM6A Antikörper)-MLL4 (zeige MLL4 Antikörper)-p300 (zeige NOTCH1 Antikörper) transcriptional regulatory network establishing an "active enhancer landscape" and defines a detailed mechanism for the joint deposition of H3K4me1 and H3K27ac.
Acetylation-dependent control of global poly(A) RNA degradation by CBP/p300 (zeige CREBBP Antikörper) and HDAC1-HDAC2 (zeige HDAC1 Antikörper) has been described.
Data, including data from studies in cells from knockout mice, suggest that Prmt1 (zeige PRMT1 Antikörper) activity was necessary for c-Myc (zeige MYC Antikörper) binding to acetyltransferase p300 (zeige NOTCH1 Antikörper) in myeloid cells; Prmt1 (zeige PRMT1 Antikörper) inhibition decreases p300 (zeige NOTCH1 Antikörper) recruitment to c-Myc (zeige MYC Antikörper) target promoters and increased Hdac1 (zeige HDAC1 Antikörper) recruitment. [Prmt1 (zeige PRMT1 Antikörper), protein arginine N-methyltransferase 1 (zeige PRMT1 Antikörper); c-Myc (zeige MYC Antikörper) = Proto-Oncogene (zeige RAB1A Antikörper) Proteins c-myc (zeige MYC Antikörper); Hdac1 (zeige HDAC1 Antikörper) = histone deacetylase 1 (zeige HDAC1 Antikörper)]
In line with the acetyltransferase activity of p300 (zeige NOTCH1 Antikörper), H3K27 acetylation was reduced after HDACi and resulted in the formation of heterochromatin in the PTGES1 gene. In conclusion, HDAC (zeige HDAC3 Antikörper) activity maintains PTGES1 expression by recruiting p300 (zeige NOTCH1 Antikörper) to its gene

p300 (EP300) Antigen-Profil

Beschreibung des Gens

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.

Alternative names and synonyms associated with p300 (EP300)

E1A binding protein p300 (EP300) Antikörper
histone acetyltransferase p300 (LOC446056) Antikörper
E1A binding protein p300 (ep300) Antikörper
E1A binding protein p300 (Ep300) Antikörper

A430090G16 Antikörper
A730011L11 Antikörper
KAT3B Antikörper
p300 Antikörper
p300 HAT Antikörper
RSTS2 Antikörper

Bezeichner auf Proteinebene für EP300

histone acetyltransferase p300 , histone acetyltransferase , E1A binding protein p300 , histone acetyltransferase p300-like , E1A-associated protein p300 , E1A-binding protein, 300kD , p300 HAT

GENE ID	SPEZIES
100055626	Equus caballus
458862	Pan troglodytes
706258	Macaca mulatta
446056	Takifugu rubripes
100028102	Monodelphis domestica
100455260	Pongo abelii
100468694	Ailuropoda melanoleuca
100543704	Meleagris gallopavo
100566746	Anolis carolinensis
2033	Homo sapiens
328572	Mus musculus
418000	Gallus gallus
100684945	Canis lupus familiaris
100156226	Sus scrofa
170915	Rattus norvegicus
100734820	Cavia porcellus

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Show all anti-E1A Binding Protein P300 (EP300) Antikörper with Pubmed References

Human E1A Binding Protein P300 (EP300) Interaktionspartner

Mouse (Murine) E1A Binding Protein P300 (EP300) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with p300 (EP300)

Bezeichner auf Proteinebene für EP300