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NOXA Proteine

(Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1))

Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.

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NOXA Protein (AA 1-103) (His tag)

custom-made PMAIP1 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Pmaip1 Protein, UniprotID Q9JM54

3 Abbildungen

Produktnummer ABIN7561692

Details

NOXA Protein (AA 1-54) (Fc Tag)

custom-made PMAIP1 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant PMAIP1 Protein, UniprotID Q13794

3 Abbildungen

Produktnummer ABIN7552197

Details

NOXA Protein (AA 1-136) (GST tag)

PMAIP1 Spezies: Human Wirt: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for Phorbol-12-Myristate-13-Acetate-Induced Protein 1 (PMAIP1) (AA 1-136) protein (GST tag) (ABIN1315507)

1 image

Produktnummer ABIN1315507

Details

NOXA Protein (AA 1-103) (Strep Tag)

custom-made PMAIP1 Spezies: Maus Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

Produktnummer ABIN3130350