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anti-Human FAS Antikörper:
anti-Mouse (Murine) FAS Antikörper:
anti-Rat (Rattus) FAS Antikörper:
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Mouse (Murine) Polyclonal FAS Primary Antibody für IHC (fro), IHC (p) - ABIN3044338
Jiang, Li, Zhou, Wang, Zhang, Wang: Colistin-induced apoptosis in PC12 cells: involvement of the mitochondrial apoptotic and death receptor pathways. in International journal of molecular medicine 2014
Show all 14 Pubmed References
Rat (Rattus) Polyclonal FAS Primary Antibody für WB - ABIN3042386
Liu, Shan, Dong, Liu, Ma, Liu: Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury. in World journal of gastroenterology 2013
Show all 13 Pubmed References
Human Polyclonal FAS Primary Antibody für IHC (p), WB - ABIN3042387
Qin, Ma, Yang, Hu, Zhou, Fu, Tian, Liu, Xu, Shen: A Triterpenoid Inhibited Hormone-Induced Adipocyte Differentiation and Alleviated Dexamethasone-Induced Insulin Resistance in 3T3-L1 adipocytes. in Natural products and bioprospecting 2015
Show all 13 Pubmed References
Human Monoclonal FAS Primary Antibody für IHC (fro), IF - ABIN1106610
Vega, Jazirehi, Huerta-Yepez, Bonavida: Rituximab-induced inhibition of YY1 and Bcl-xL expression in Ramos non-Hodgkin's lymphoma cell line via inhibition of NF-kappa B activity: role of YY1 and Bcl-xL in Fas resistance and chemoresistance, respectively. in Journal of immunology (Baltimore, Md. : 1950) 2005
Show all 16 Pubmed References
Human Monoclonal FAS Primary Antibody für FACS - ABIN5541252
Hata, Matsuzaki, Takeya, Yoshida, Sonoki, Nagasaki, Kuribayashi, Kawano, Takatsuki: Expression of Fas/Apo-1 (CD95) and apoptosis in tumor cells from patients with plasma cell disorders. in Blood 1995
Show all 12 Pubmed References
Human Monoclonal FAS Primary Antibody für FACS - ABIN5541251
Boirivant, Pica, DeMaria, Testi, Pallone, Strober: Stimulated human lamina propria T cells manifest enhanced Fas-mediated apoptosis. in The Journal of clinical investigation 1997
Show all 12 Pubmed References
Mouse (Murine) Monoclonal FAS Primary Antibody für CyTox, FACS - ABIN1177304
Enari, Hug, Nagata: Involvement of an ICE-like protease in Fas-mediated apoptosis. in Nature 1995
Show all 9 Pubmed References
Mouse (Murine) Monoclonal FAS Primary Antibody für FACS - ABIN2689463
Hiromatsu, Aoki, Makino, Matsumoto, Mizuochi, Gotoh, Nomoto, Ogasawara, Nagata, Yoshikai: Increased Fas antigen expression in murine retrovirus-induced immunodeficiency syndrome, MAIDS. in European journal of immunology 1994
Show all 9 Pubmed References
Human Polyclonal FAS Primary Antibody für IHC, IHC (p) - ABIN448412
Horuz, Göktaş, Çetinel, Akça, Aydın, Ekici, Albayrak, Sarıca: Role of TNF-associated cytokines in renal tubular cell apoptosis induced by hyperoxaluria. in Urolithiasis 2013
Show all 6 Pubmed References
Mouse (Murine) Monoclonal FAS Primary Antibody für CyTox, FACS - ABIN2689461
Kägi, Vignaux, Ledermann, Bürki, Depraetere, Nagata, Hengartner, Golstein: Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. in Science (New York, N.Y.) 1994
Show all 5 Pubmed References
The mRNA expression of FAS was lower in patients with TP53 (zeige TP53 Antikörper) mutation than TP53 (zeige TP53 Antikörper) wild-type. Our findings suggest that TP53 (zeige TP53 Antikörper) mutation is a potential negative predictor of metastatic melanoma treated with CTLA-4 (zeige CTLA4 Antikörper) blockade.
Complete local landscape for a defined molecular function-the alternative splicing of an exon (FAS/CD95 exon 6). The extensive epistasis in the landscape predicts that exonic regulatory sequences may diverge between species even when exon inclusion levels are functionally important and conserved by selection.
Paper analyses results of serum cytokines and lymphocyte apoptosis study in nodular goiter against the background of autoimmune thyroiditis and thyroid adenoma based on the cell preparedness to apoptosis, the number of apoptotic lymphocytes and the content of proapoptotic tumor necrosis factor-alpha, interleukins in serum, considering the polymorphism of BCL-2, CTLA-4 and APO-1 genes.
These results demonstrated that overexpression of ING4 (zeige ING4 Antikörper) can induce the apoptosis of melanoma cells and CD3 (zeige CD3 Antikörper)+ T cells through signaling pathways such as the Fas/FasL (zeige FASL Antikörper) pathway, and that ING4 (zeige ING4 Antikörper) gene therapy for melanoma treatment is a novel approach.
Tag7 (zeige PGLYRP1 Antikörper) activates lymphocytes capable of Fasl (zeige FASL Antikörper)-Fas-dependent contact killing of virus-infected cells.
These results indicated that cMyc (zeige MYC Antikörper) and Fas regulated the sensitivity of A549 cells to irradiation by regulating caspase8-mediated Bid (zeige BID Antikörper) activation and the subsequent association with the mitochondrial pathway of apoptosis.
this study characterized in juvenile systemic lupus erythematosus a distinct profile from adult SLE that comprises increased sFas, sTRAIL, and reduced sFasL (zeige FASL Antikörper), notably in patients with active disease and with nephritis.
results from the current study showed that the association of FAS-670A/G SNP with idiopathic azoospermia was not found in a population of men with idiopathic infertility.
The Btk (zeige BTK Antikörper)-dependent PIP5K1gamma lipid kinase activation by Fas counteracts FasL (zeige FASL Antikörper)-induced cell death.
Study identify genes highly expressed in Kras knockout lung cancer cells, including the Fas receptor gene. Antibodies that activate Fas receptor selectively induced apoptosis in Kras-independent lung cancer cells suggesting that FAS is involved in KRAS-related drug resistance.
Messenger RNA and protein levels of prostaglandin (PG) E synthase (PGES (zeige PTGES Antikörper)), PGF2alpha receptor (PGFR), tumor necrosis factor-alpha (TNF (zeige TNF Antikörper)) and Fas were found to be higher in the corpus luteum of pregnancy than in corpus luteum of the cycle.
Results did not support that K8/K18 (zeige KRT18 Antikörper) filaments influence the expression of Fas on the surface of luteal cells.
activation of the Fas pathway and presence of FSH (zeige BRD2 Antikörper) during in vitro maturation increased the incidence of apoptosis in cumulus cells
demonstrated for the first time that normal ejaculated spermatozoa express Fas antigen (zeige FASL Antikörper); data showed that a large percentage of normal ejaculated spermatozoa of fertile bulls are immunocytochemically positive for Fas
identification of 14-3-3zeta (zeige YWHAZ Antikörper) as a novel phosphocofilin binding protein involved in the maintenance of the cellular phosphocofilin pool
TPD7 altered the extrinsic apoptosis pathway by upregulating Fas expression.
In conclusion, these data demonstrate that murine herpesvirus 68-immortalized SL-1 (zeige MMP3 Antikörper) cells can be recognized and controlled by specific cytotoxic T cells through CD95/CD95L (zeige FASL Antikörper)-mediated apoptosis.
Findings indicate that induction of apoptosis through Fas is dependent on receptor palmitoylation in primary immune cells, and Fas may prevent autoimmunity by mechanisms other than inducing apoptosis.
Both Sharpin (zeige SHARPIN Antikörper)/Fas and Sharpin (zeige SHARPIN Antikörper)/Fasl (zeige FASL Antikörper) compound mutant mice developed an auto-inflammatory phenotype similar to that seen in Sharpin (zeige SHARPIN Antikörper) null mice, indicating that initiation of apoptosis by FAS signalling is likely not involved in the pathogenesis of this disease.
leucine deprivation induces the expression of miR (zeige MLXIP Antikörper)-212-5p in a GCN2 (zeige EIF2AK4 Antikörper)/ATF4 (zeige ATF4 Antikörper)-dependent manner. miR (zeige MLXIP Antikörper)-212-5p suppresses lipid accumulation in liver by targeting FAS and SCD1 (zeige SCD Antikörper) under both normal diet and high-fat diet conditions.
Our data show that loss of Fas activity strongly affects the early development of atopic dermatitis (AD) by leading to Th2-dominant inflammation characterized by dermal infiltration of CD4 (zeige CD4 Antikörper)+ T cells, neutrophils and increased skin expression of Th2 cytokines.However, Fas/FasL (zeige FASL Antikörper)-apoptotic pathway is also involved in restricting tissue remodelling and dermal fibrosis during AD.
Hrd1 (zeige SYVN1 Antikörper)-null B cells exhibited high Fas expression during activation and rapidly underwent Fas-mediated apoptosis, which could be largely inhibited by FasL (zeige FASL Antikörper) neutralization. Fas mutation in Hrd1 (zeige SYVN1 Antikörper) KO mice abrogated the increase in B-cell AICD. We identified Hrd1 (zeige SYVN1 Antikörper) as the first E3 ubiquitin ligase (zeige MUL1 Antikörper) of the death receptor Fas and Hrd1 (zeige SYVN1 Antikörper)-mediated Fas destruction as a molecular mechanism in regulating B-cell immunity.
FAS contributes to mitochondrial dysfunction, steatosis development, and insulin (zeige INS Antikörper) resistance under high fat diet.
anti-apoptotic molecules BclxL (zeige BCL2L1 Antikörper) and Bcl-2 (zeige BCL2 Antikörper) and the pro-apoptotic factors BAD and BID (zeige BID Antikörper) cooperate to promote migration of triple-negative breast cancer cells stimulated with cl-CD95L (zeige FASL Antikörper).
Fas was expressed on fetal pig pancreatic cells, both beta and non-beta cells, and the level of expression could be upregulated by exposure to interleukin 1beta
The expression of FAS and FAS ligand (zeige FASL Antikörper) in splenic macrophages co-infected with porcine circovirus 2 and porcine reproductive and respiratory syndrome virus is reported
The present results may provide some insights to understand the role of Fas/FasL (zeige FASL Antikörper) in the spinal cord but not motor cortex with neuronal apoptosis and neuroplasticity in monkeys subjected to hemisection spinal cord injury.
Ligustrazine has notable protective effects on pulmonary ischemia/reperfusion injury inhibiting Fas/FasL (zeige FASL Antikörper) mRNA express in lung tissue and decreasing apoptosis.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.
APO-1 cell surface antigen
, CD95 antigen
, Delta Fas/APO-1/CD95
, FAS 827dupA
, FASLG receptor
, Fas (TNF receptor superfamily, member 6)
, Fas AMA
, TNF receptor superfamily member 6
, apoptosis antigen 1
, apoptosis-mediating surface antigen FAS
, tumor necrosis factor receptor superfamily member 6
, tumor necrosis factor receptor superfamily, member 6
, Fas antigen
, 14-3-3 protein zeta/delta
, factor activating exoenzyme S
, protein kinase C inhibitor protein 1
, Fas (TNF receptor superfamily member)
, apo-1 antigen
, Fas antigen (ATP1)
, Fas receptor
, Tumor necrosis factor receptor superfamily, member 6
, apoptosis (APO-1) antigen 1 ( FAS ), member 6
, Fas receptor CD95