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anti-Human C-MYC Antikörper:
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Human Monoclonal C-MYC Primary Antibody für FM, IHC (fro) - ABIN967320
Blackwood, Eisenman: Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc. in Science (New York, N.Y.) 1991
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Human Monoclonal C-MYC Primary Antibody für FACS, IHC (p) - ABIN302092
Veracini, Simon, Richard, Schraven, Horejsi, Roche, Benistant: The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1. in The Journal of cell biology 2008
Show all 14 Pubmed References
Human Monoclonal C-MYC Primary Antibody für FACS, IHC (p) - ABIN302017
Wang, Campoli, Ko, Luo, Ferrone: Enhancement of scFv fragment reactivity with target antigens in binding assays following mixing with anti-tag monoclonal antibodies. in Journal of immunological methods 2004
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All Species Monoclonal C-MYC Primary Antibody für FACS, IP - ABIN2749043
Persson, Hennighausen, Taub, DeGrado, Leder: Antibodies to human c-myc oncogene product: evidence of an evolutionarily conserved protein induced during cell proliferation. in Science (New York, N.Y.) 1984
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Chicken Monoclonal C-MYC Primary Antibody für ChIP, CyTOF - ABIN152253
Locker, Dowle, Ellis, Elston, Blamey, Sikora, Evan, Robins: c-myc oncogene product expression and prognosis in operable breast cancer. in British journal of cancer 1989
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All Species Monoclonal C-MYC Primary Antibody für IHC, IHC (p) - ABIN4994828
Hilpert, Hansen, Wessner, Küttner, Welfle, Seifert, Höhne: Anti-c-myc antibody 9E10: epitope key positions and variability characterized using peptide spot synthesis on cellulose. in Protein engineering 2001
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Human Monoclonal C-MYC Primary Antibody für IHC (fro), IF - ABIN2477762
Quant, Woo: Normal values of eye position in the Chinese population of Hong Kong. in Optometry and vision science : official publication of the American Academy of Optometry 1992
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Human Monoclonal C-MYC Primary Antibody für FACS, IHC (p) - ABIN4369572
Fujiwara, Poikonen, Aleman, Valtavaara, Saksela, Mayer: A single-chain antibody/epitope system for functional analysis of protein-protein interactions. in Biochemistry 2002
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Human Polyclonal C-MYC Primary Antibody für IF (cc), IF (p) - ABIN1387773
Gao, Zhao, Song, Yang: Expression pattern of embryonic stem cell markers in DFAT cells and ADSCs. in Molecular biology reports 2012
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Here the authors show that sublethal activation of Caspase-3 (zeige CASP3 Antikörper) plays an essential, facilitative role in Myc-induced genomic instability and oncogenic transformation.
Our findings indicate that Prdx2 (zeige PRDX2 Antikörper) might have an important role in the regulation of trophoblast proliferation and apoptosis during early pregnancy, and that its expression is mediated by c-Myc. Thus, these two proteins may be involved in the pathogenesis of RM and may represent potential therapeutic targets
Our results indicate that AURKA (zeige AURKA Antikörper) plays an important role in the activation of EIF4E (zeige EIF4E Antikörper) and cap-dependent translation. Targeting the AURKA (zeige AURKA Antikörper)-EIF4E (zeige EIF4E Antikörper)-c-MYC axis using alisertib is a novel therapeutic strategy that can be applicable for everolimus-resistant tumors and/or subgroups of cancers that show overexpression of AURKA (zeige AURKA Antikörper) and activation of EIF4E (zeige EIF4E Antikörper) and c-MYC
MYC and hsamiR4235p have been identified to be critical biomarkers in nasopharyngeal carcinoma.
Taken together, this study suggests that the OVOL1 (zeige OVOL1 Antikörper)-OVOL2 (zeige OVOL2 Antikörper) axis is a key modulator of c-Myc expression in the shift from in situ epidermal malignancy (Bowen's disease) to invasive squamous cell carcinoma.
This study identified PDIA3P as a novel c-Myc interacting long noncoding RNA.
Epstein-Barr virus super-enhancers eRNAs important for enhancer-promoter looping at the MYC locus
MYC expression significantly correlated with PD-L1 (zeige CD274 Antikörper) expression and NSCLC patients with MYC-PD-L1 (zeige CD274 Antikörper) double-positive samples showed poor clinical outcomes.
The lower apoptotic activity of low-grade slightly elevated adenomas can be partly attributed to upregulated beta-catenin (zeige CTNNB1 Antikörper) pathway activity and downregulated c-Myc expression.
Inhibition of mitochondrial translation with the antibiotic Tigecycline was synthetic-lethal with Myc activation, impaired respiratory activity and tumor cell survival in vitro, and significantly extended lifespan in lymphoma-bearing mice.
Ouabain-induced proliferation might be attributed, at least in part, to decrease of intracellular free calcium and increase of c-myc mRNA expression, and that may be directly or indirectly involved in regulation of blood pressure.
report the isolation of complete coding regions of rabbit SOX2, KLF4, C-MYC and NANOG, which encode transcription factors that play crucial regulatory roles during early mammalian embryonic development
AKAP1 (zeige AKAP1 Antikörper) is a transcriptional target of Myc, and it supports mTOR (zeige FRAP1 Antikörper) pathway and the growth of cancer cells.
Spermatogonial stem cells and progenitors are refractory to reprogramming to pluripotency by the transcription factors Oct3/4 (zeige POU5F1 Antikörper), c-Myc, Sox2 (zeige SOX2 Antikörper) and Klf4 (zeige KLF4 Antikörper).
High c-myc expression is associated with gliomagenesis.
In a mouse lung model of KRas(G12D)-driven adenomas, co-activation of Myc drives the immediate transition to highly proliferative and invasive adenocarcinomas marked by highly inflammatory, angiogenic, and immune-suppressed stroma.
the role of phosphorylation on AID serine38 in AID activity at the Immunoglobulin switch region and off-target Myc gene, is reported.
This study demonstrates that LMP2A uses the role of MYC in the cell cycle, particularly in the p27(kip1 (zeige CDKN1B Antikörper)) degradation process, to accelerate lymphomagenesis in vivo.
Results show Myc to be dispensable for sustained in vivo hepatocyte proliferation but necessary for maintaining normal lipid homeostasis.
Data show that the induction of BIM (zeige BCL2L11 Antikörper) in the MYC- and RAS-driven leukemia is mediated by the downregulation of miR-17-92, and suggest that induction of BIM (zeige BCL2L11 Antikörper)-mediated apoptosis may be a therapeutic approach for acute lymphoblastic leukemia (ALL).
Pin1 (zeige PIN1 Antikörper) silencing in lymphomas retarded disease progression in mice, making Pin1 (zeige PIN1 Antikörper) an attractive therapeutic target in Myc-driven tumors.
beta-catenin (zeige CTNNB1 Antikörper) cooperates with the transcription factor Myc to activate the progenitor renewal program.
Apoptosis was also observed with myca expression; introduction of homozygous tp53 (zeige TP53 Antikörper)(-/-) mutation into the myca transgenic fish reduced apoptosis and accelerated tumor progression.
MYC down-regulation induces mitochondrial apoptosis in T lymphoblasts.
These findings not only reveal a novel role of Mad1 (zeige MXD1 Antikörper) in regulating developmental cell death but also suggest that a balance of Mad and Myc controls cell fate determination during adult organ development.
Thyroid hormone (zeige PTH Antikörper) activates protein arginine methyltransferase 1 expression by directly inducing c-Myc transcription during Xenopus intestinal stem cell development.(
c-Myc has a direct role in the control of DNA replication
Findings support a model in which Myc, Twist and Slug/Snail2 function in a regulatory circuit within lateral plate mesoderm that directs normal vessel formation in both the vascular and lymphatic systems.
Expression of Drosophila Myc (dMyc) suppresses, whereas loss of dMyc enhances, ectopically activated JNK (zeige MAPK8 Antikörper) signaling-induced cell death. dMyc impedes physiologically activated JNK (zeige MAPK8 Antikörper) pathway-mediated cell death. Loss of dMyc triggers JNK (zeige MAPK8 Antikörper) pathway activation and JNK (zeige MAPK8 Antikörper)-dependent cell death.
tissue-specific downregulation of the Drosophila homolog of human c-myc proto-oncogene (dMyc) suppresses tau-mediated morphological and functional deficits by reducing abnormal tau hyperphosphorylation and restoring the heterochromatin loss.
dMyc has an essential role in preventing JNK (zeige MAPK8 Antikörper)-mediated retinal glial activation
the key target of the Psi/MED network in controlling developmentally regulated tissue growth is the transcription factor MYC.
Myc dosage plays crucial role in determining sex-specific size in Drosophila larvae and adult tissue. Double dose of Myc in females serves at least twice in development to promote sexual size dimorphism.
BicC (zeige BICC1 Antikörper) down regulates Myc in the Malpighian tubule.
activation of the TOR-Myc axis in midgut stem and progenitor cells influences a variety of traits in Drosophila
Drosophila adult muscle precursors display homing behavior to muscle niche and the niche-driven Insulin (zeige INS Antikörper)-Notch (zeige NOTCH1 Antikörper)-dMyc cascade plays a key role in setting the activated state of adult muscle precursors.
a functional link between Myc, a renowned oncogene (zeige RAB1A Antikörper), and the essential nucleotide biosynthetic enzyme CTPsyn.
MYC and S6K (zeige RPS6KB1 Antikörper) cooperate through coordinate activation of the essential Pol I transcription initiation factor TIF-1A (zeige RRN3 Antikörper).
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
avian myelocytomatosis viral oncogene homolog
, class E basic helix-loop-helix protein 39
, myc proto-oncogene protein
, myc-related translation/localization regulatory factor
, proto-oncogene c-Myc
, transcription factor p64
, v-myc myelocytomatosis viral oncogene homolog
, c-myc proto-oncogene
, avian myelocytomatosis viral (v-myc) oncogene homolog
, Avian myelocytomatosis viral (v-myc) oncogene homolog
, myelocytomatosis viral oncogene homolog
, v-myc avian myelocytomatosis viral oncogene homolog
, cellular myelocytomatosis oncogene
, Proto-oncogene c-Myc
, Transcription factor p64
, transcriptional regulator Myc-A
, MYC II
, transcriptional regulator Myc-B
, Myc proto-oncogene protein
, CG10798 gene product from transcript CG10798-RB
, Diminutive protein
, lethal (1) G0354
, lethal (1) G0359