Osteopontin Proteine
(Secreted phosphoprotein 1 (SPP1))
The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
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SPP1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SPP1
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SPP1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
SPP1
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
SPP1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
90 %
ELISA
1 image
3 Referenzen
SPP1
Spezies: Human
Wirt: Escherichia coli (E. coli)
> 95 %
AcA, CC
Active
2 Abbildungen
SPP1
Spezies: Ratte
Wirt: HEK-293 Cells
> 95 %
AcA, CC
Active
2 Abbildungen
SPP1
Spezies: Schwein
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SPP1
Spezies: Human
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SPP1
Spezies: Cynomolgus
Wirt: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SPP1
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 85 %
WB, SDS, Imm, PC
SPP1
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 87 % by SDS-PAGE.
Active
SPP1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
SPP1
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
SPP1
Spezies: Maus
Wirt: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, Imm, ELISA, AcA
Active
SPP1
Spezies: Human
Wirt: Mammalian Cells
Recombinant
>90 % as determined by SDS-PAGE.
WB, SDS, Imm, ELISA, AcA
Active
SPP1
Spezies: Rind (Kuh)
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
SPP1
Spezies: Schwein
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
SPP1
Spezies: Kaninchen
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
Aktuelle Publikationen für unsere Osteopontin Proteine
: "Inhibition of calcium oxalate crystal growth in vitro by uropontin: another member of the aspartic acid-rich protein superfamily." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 1, pp. 426-30, (1992) (PubMed).: "cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN)." in: Genomics, Vol. 7, Issue 4, pp. 491-502, (1990) (PubMed).
: "The cDNA and derived amino acid sequence for human osteopontin." in: Nucleic acids research, Vol. 17, Issue 8, pp. 3306, (1989) (PubMed).
Aliase für Osteopontin Proteine
secreted phosphoprotein 1 (SPP1) Proteinesecreted phosphoprotein 1 (Spp1) Proteine
secreted phosphoprotein 1 (spp1) Proteine
2AR Proteine
Apl-1 Proteine
BNSP Proteine
Bsp Proteine
BSPI Proteine
Eta Proteine
ETA-1 Proteine
OP Proteine
OPN Proteine
Opn Proteine
Opnl Proteine
OSP Proteine
Ric Proteine
Spp-1 Proteine
zgc:111821 Proteine
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