This gene was originally cloned from human myeloblasts and found to be selectively expressed in inflammed colonic epithelium. This gene encodes a member of the olfactomedin family. The encoded protein is an antiapoptotic factor that promotes tumor growth and is an extracellular matrix glycoprotein that facilitates cell adhesion. [provided by RefSeq, Mar 2011].
Aktuelle Publikationen für unsere Olfactomedin 4 Proteine
Zhao, Shu, Duan, Wang, Min, Shen, Ruan, Qin, Sun, Qin: "Loss of OLFM4 promotes tumor migration through inducing interleukin-8 expression and predicts lymph node metastasis in early gastric cancer." in: Oncogenesis, Vol. 5, Issue 6, pp. e234, (2016) (PubMed).
Gersemann, Becker, Nuding, Antoni, Ott, Fritz, Oue, Yasui, Wehkamp, Stange: "Olfactomedin-4 is a glycoprotein secreted into mucus in active IBD." in: Journal of Crohn's & colitis, Vol. 6, Issue 4, pp. 425-34, (2012) (PubMed).