NR0B2 ELISA Kits

Protein Überblick

The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function.

Alternative names and synonyms associated with NR0B2

• nuclear receptor subfamily 0 group B member 2 (NR0B2) Antikörper
• nuclear receptor subfamily 0, group B, member 2 (Nr0b2) Antikörper
• nuclear receptor subfamily 0, group B, member 2a (nr0b2a) Antikörper

• gb:bc058069 Antikörper
• Nr0b2 Antikörper
• NR0B2-A Antikörper
• Shp Antikörper
• SHP-1 Antikörper
• Alle Synonyme
• SHP-A Antikörper
• Shp1 Antikörper

Bezeichner auf Proteinebene für NR0B2

short heterodimer partner , nuclear receptor subfamily 0 group B member 2 , nuclear receptor SHP , orphan nuclear receptor SHP , small heterodimer partner , small heterodimer partner homologue