NUP98 Produkte
(Nucleoporin 98kDa (NUP98))
Kategorien
Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromosome translocations in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants\; however, not all variants have been fully described. [provided by RefSeq, May 2010].
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Ausgewählte NUP98 Kategorien
NUP98 Antikörper
High quality antibodies with extensive validation data.
NUP98 ELISA Kits
Reliable ELISA kits for a wide range of species.
NUP98 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NUP98 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena
Applikation
WB, IF
Validierungen
- (2)
- (8)
Kat. Nr.
ABIN2452064
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Tetrahymena
Applikation
WB, IF
Validierungen
- (2)
- (8)
Kat. Nr.
ABIN2452065
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat, Saccharomyces cerevisiae, Schizosaccharomyces pombe
Applikation
WB, ELISA, IF, ICC, DB
Validierungen
- (2)
- (14)
Kat. Nr.
ABIN2452066
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene NUP98 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN1116273
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Cow
Analytical Method
Quantitative
Validierungen
Kat. Nr.
ABIN994229
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Sheep
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1056665
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NUP98 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313246
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313248
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7578586
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NUP98 Produkten
: "NPHP proteins are binding partners of nucleoporins at the base of the primary cilium." in: PLoS ONE, Vol. 14, Issue 9, pp. e0222924, (2019) (PubMed).: "Widespread intronic polyadenylation inactivates tumour suppressor genes in leukaemia." in: Nature, Vol. 561, Issue 7721, pp. 127-131, (2018) (PubMed).
: "Tpr regulates the total number of nuclear pore complexes per cell nucleus." in: Genes & development, Vol. 32, Issue 19-20, pp. 1321-1331, (2018) (PubMed).
: "Evolution of a transcriptional regulator from a transmembrane nucleoporin." in: Genes & development, Vol. 30, Issue 10, pp. 1155-71, (2016) (PubMed).
: "Monoclonal antibodies recognize gly-leu-phe-gly repeat of nucleoporin nup98 of tetrahymena, yeasts, and humans." in: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 2, pp. 81-90, (2013) (PubMed).
: "Nucleoporin Nup98: a gatekeeper in the eukaryotic kingdoms." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 15, Issue 7, pp. 661-9, (2010) (PubMed).
: "Specific monoclonal antibody against the nuclear pore complex protein, nup98." in: Hybridoma (2005), Vol. 24, Issue 5, pp. 244-7, (2005) (PubMed).
Synonyme und alternative Namen zu NUP98
Nucleoporin 98-96kD (Nup98-96), nuclear pore complex protein Nup98-Nup96 (LOC408335), nucleoporin 98 (NUP98), nuclear pore complex protein Nup98-Nup96 (LOC587580), nucleoporin 98kDa (NUP98), nucleoporin 98 (Nup98), nucleoporin 98 (nup98), nucleoporin 98 L homeolog (nup98.L), 4732457F17, ADIR2, AI849286, CG10198, CG10201, Dmel\\CG10198, GB12688, im:7151238, l(3)95BCd, Nup-98, Nup 96, Nup96, NUP96, Nup 98, Nup98, NUP98, nup98-96, Nup98-Nup96, Nup98/96, nup145, NUP196, zgc:63593, zgc:113968Bezeichner auf Proteinebene für NUP98
- CG10198-PA
- CG10198-PC
- CG10198-PD
- Nup98
- Nup98-96-PA
- Nup98-96-PC
- Nup98-96-PD
- nucleoporin 98
- nucleoporin 98-96
- nucleoporin98-96
- nucleoporin 98kD
- nucleoporin 98kDa
- nuclear pore complex protein Nup98-Nup96-like
- nuclear pore complex protein Nup98-Nup96
- 98 kDa nucleoporin
- nuclear pore complex protein Nup98
- nucleoporin Nup98
- GLFG-repeat containing nucleoporin
- Nup98-Nup96
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