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NUB1 Produkte

(Negative Regulator of Ubiquitin-Like Proteins 1 (NUB1))

Kategorien

This gene encodes a protein that functions as a negative regulator of NEDD8, a ubiquitin-like protein that conjugates with cullin family members in order to regulate vital biological events. The protein encoded by this gene regulates the NEDD8 conjugation system post-transcriptionally by recruiting NEDD8 and its conjugates to the proteasome for degradation. This protein interacts with the product of the AIPL1 gene, which is associated with Leber congenital amaurosis, an inherited retinopathy, and mutations in that gene can abolish interaction with this protein, which may contribute to the pathogenesis. This protein is also known to accumulate in Lewy bodies in Parkinson's disease and dementia with Lewy bodies, and in glial cytoplasmic inclusions in multiple system atrophy, with this abnormal accumulation being specific to alpha-synucleinopathy lesions. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011].

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Ausgewählte NUB1 Kategorien

NUB1 Antikörper

High quality antibodies with extensive validation data.

NUB1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NUB1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Dog, Human, Monkey, Rat
Applikation WB, IHC, IHC (p), IF, FACS
Validierungen
  • (7)
Kat. Nr. ABIN1490743
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN389078
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human, Monkey, Mouse
Applikation WB, IHC, ELISA, IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN6263785
Menge 100 μL
Datenblatt Datenblatt

Empfohlene NUB1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1381369
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Cow
Analytical Method
Validierungen
Kat. Nr. ABIN1144444
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NUB1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1313137
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1313139
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3084737
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NUB1 Produkten

Tanaka, Kawashima, Yeh, Kamitani: "Regulation of the NEDD8 conjugation system by a splicing variant, NUB1L." in: The Journal of biological chemistry, Vol. 278, Issue 35, pp. 32905-13, (2003) (PubMed).

Akey, Zhu, Dyer, Li, Sorensen, Blackshaw, Fukuda-Kamitani, Daiger, Craft, Kamitani, Sohocki: "The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1." in: Human molecular genetics, Vol. 11, Issue 22, pp. 2723-33, (2002) (PubMed).

Kito, Yeh, Kamitani: "NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression." in: The Journal of biological chemistry, Vol. 276, Issue 23, pp. 20603-9, (2001) (PubMed).

Synonyme und alternative Namen zu NUB1

negative regulator of ubiquitin-like proteins 1 (Nub1), negative regulator of ubiquitin like proteins 1 (NUB1), 4931404D21Rik, 6330412F12Rik, BS4, NUB1L, NY-REN-18, NYREN18

Bezeichner auf Proteinebene für NUB1

  • NEDD8 ultimate buster 1
  • NEDD8 ultimate buster-1
  • NY-REN-18 antigen
  • renal carcinoma antigen NY-REN-18
  • Nedd8 ultimate buster-1
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