NSD1 Produkte
(Nuclear Receptor Binding SET Domain Protein 1 (NSD1))
Kategorien
This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte NSD1 Kategorien
NSD1 Antikörper
High quality antibodies with extensive validation data.
Empfohlene NSD1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN528606
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN872593
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (1)
Kat. Nr.
ABIN7191723
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene NSD1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124211
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1313060
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NSD1 Produkten
: "The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells." in: Molecular cell, Vol. 70, Issue 2, pp. 371-379.e5, (2018) (PubMed).: "Community resources and technologies developed through the NIH Roadmap Epigenomics Program." in: Methods in molecular biology (Clifton, N.J.), Vol. 1238, pp. 27-49, (2014) (PubMed).
: "A transposon-based analysis of gene mutations related to skin cancer development." in: The Journal of investigative dermatology, Vol. 133, Issue 1, pp. 239-48, (2013) (PubMed).
: "Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 1, pp. 46-51, (2010) (PubMed).
Synonyme und alternative Namen zu NSD1
nuclear receptor binding SET domain protein 1 (NSD1), nuclear receptor binding SET domain protein 1 (nsd1), nuclear receptor binding SET domain protein 1 (Nsd1), histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (LOC540197), nuclear receptor-binding SET-domain protein 1 (Nsd1), AI528500, ara267, ARA267, kmt3b, KMT3B, NSD1, sotos, SOTOS, SOTOS1, sto, STOBezeichner auf Proteinebene für NSD1
- nuclear receptor binding SET domain protein 1
- histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific-like
- H3-K36-HMTase
- H4-K20-HMTase
- NR-binding SET domain-containing protein
- androgen receptor coactivator 267 kDa protein
- androgen receptor-associated coregulator 267
- androgen receptor-associated protein of 267 kDa
- histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific
- lysine N-methyltransferase 3B
- nuclear receptor-binding SET domain-containing protein 1
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