NOD1 Produkte
(Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
Kategorien
This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Oct 2009].
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Ausgewählte NOD1 Kategorien
NOD1 Antikörper
High quality antibodies with extensive validation data.
NOD1 ELISA Kits
Reliable ELISA kits for a wide range of species.
NOD1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene NOD1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (5)
Kat. Nr.
ABIN3021838
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, IHC (p), ICC
Validierungen
- (6)
Kat. Nr.
ABIN3032080
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p)
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN872332
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene NOD1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6974816
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1145825
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NOD1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312757
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312759
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312761
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NOD1 Produkten
: "Evodiamine Induces Apoptosis in SMMC-7721 and HepG2 Cells by Suppressing NOD1 Signal Pathway." in: International journal of molecular sciences, Vol. 19, Issue 11, (2019) (PubMed).: "Functional Roles of NOD1 in Odontoblasts on Dental Pulp Innate Immunity." in: BioMed research international, Vol. 2016, pp. 9325436, (2016) (PubMed).
: "Cdx2 Expression and Intestinal Metaplasia Induced by H. pylori Infection of Gastric Cells Is Regulated by NOD1-Mediated Innate Immune Responses." in: Cancer research, Vol. 76, Issue 5, pp. 1135-45, (2016) (PubMed).
: "The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior." in: Molecular psychiatry, Vol. 22, Issue 2, pp. 257-266, (2016) (PubMed).
: "Proteasome particle-rich structures are widely present in human epithelial neoplasms: correlative light, confocal and electron microscopy study." in: PLoS ONE, Vol. 6, Issue 6, pp. e21317, (2011) (PubMed).
: "Hepatocytes express functional NOD1 and NOD2 receptors: a role for NOD1 in hepatocyte CC and CXC chemokine production." in: Journal of hepatology, Vol. 53, Issue 4, pp. 693-701, (2010) (PubMed).
: "Association of NOD1 (CARD4) insertion/deletion polymorphism with susceptibility to IBD: a meta-analysis." in: World journal of gastroenterology, Vol. 16, Issue 34, pp. 4348-56, (2010) (PubMed).
: "Olfactomedin 4 down-regulates innate immunity against Helicobacter pylori infection." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 24, pp. 11056-61, (2010) (PubMed).
: "Differential expression and regulation of nuclear oligomerization domain proteins NOD1 and NOD2 in human endometrium: a potential role in innate immune protection and menstruation." in: Molecular human reproduction, Vol. 15, Issue 5, pp. 311-9, (2009) (PubMed).
: "Bacterial peptide recognition and immune activation facilitated by human peptide transporter PEPT2." in: American journal of respiratory cell and molecular biology, Vol. 39, Issue 5, pp. 536-42, (2008) (PubMed).
Synonyme und alternative Namen zu NOD1
nucleotide binding oligomerization domain containing 1 (NOD1), nucleotide-binding oligomerization domain containing 1 (Nod1), C230079P11, CARD4, Card4, CLR7.1, F830007N14Rik, NLRC1, Nlrc1, RGD1562269Bezeichner auf Proteinebene für NOD1
- NLR family, CARD domain containing 1
- caspase recruitment domain family, member 4
- caspase recruitment domain-containing protein 4
- nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 1
- nucleotide-binding oligomerization domain-containing protein 1
- caspase recruitment domain 4
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