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NF-kB p65 Proteine

(Nuclear Factor-kB p65 (NFkBP65))
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].

18 Treffer

NFkBP65 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
Pubmed 25 Referenzen
Produktnummer ABIN2730698
 
custom-made NFkBP65 Spezies: Maus Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7563593
 
custom-made NFkBP65 Spezies: Human Wirt: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Produktnummer ABIN7555718
 
NFkBP65 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Pubmed 1 reference
Produktnummer ABIN1317783
 
NFkBP65 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AP, AA
Produktnummer ABIN1317785
 
NFkBP65 Spezies: Human Wirt: Insect cells (Sf21) Recombinant >95 % (SDS-PAGE) SDS Active
Produktnummer ABIN2745768
 
NFkBP65 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Produktnummer ABIN7579209
 
NFkBP65 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant WB, SDS, ELISA
Produktnummer ABIN7579208
 
NFkBP65 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
Produktnummer ABIN7391324
 
NFkBP65 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC
Produktnummer ABIN7391327
 
NFkBP65 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 85 % as determined by reducing SDS-PAGE.
Produktnummer ABIN7198860
 
NFkBP65 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
Produktnummer ABIN7391321
 
NFkBP65 Spezies: Zebrafisch (Danio rerio) Wirt: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
Produktnummer ABIN7424713
 
custom-made NFkBP65 Spezies: Maus Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
Produktnummer ABIN3134825
 
custom-made NFkBP65 Spezies: Human Wirt: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA
Produktnummer ABIN3095820
 
NFkBP65 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant WB, ELISA
Produktnummer ABIN2669407
 
NFkBP65 Spezies: Maus Wirt: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Produktnummer ABIN3012211
 
NFkBP65 Spezies: Ratte Wirt: Escherichia coli (E. coli) Recombinant WB, SDS
Produktnummer ABIN6383583
 
  • Typ Protein
    • Protein
  • Anwendung
    • Western Blotting (WB)
    • SDS-PAGE (SDS)
    • ELISA
    • Immunogen (Imm)
    • Positive Control (PC)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Antibody Production (AbP)
    • Functional Studies (Func)
    • Immunoprecipitation (IP)
    • Protein Interaction (PI)
    • Standard (STD)
  • Reaktivität
    • Human
    • Mouse
    • Rat
    • Zebrafish (Danio rerio)
  • In Publikationen zitiert
  • Abbildungen verfügbar
  • Carrier free only
  • Wirt
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Cell-free protein synthesis (CFPS)
    • Wheat germ
    • Insect cells (Sf21)
  • Bindungsspezifität
    • AA 1-549
    • AA 1-551
    • AA 19-306
    • AA 1-220
    • AA 15-189
    • AA 432-505
    • C-Term
    • Transcript Variant 1
    • full length
  • Konjugat
    • His tag
    • GST tag
    • Unkonjugiert
    • Strep Tag
    • Myc-DYKDDDDK Tag
  • Protein-Typ
    • Recombinant
  • Format
    • Liquid
    • Lyophilized
  • Biologische Aktivität
    • Biologically Active
  • Grade
    • custom-made
  • Hersteller
    • antibodies-online
    • Abbexa
    • Active Motif
    • OriGene

Aktuelle Publikationen für unsere NF-kB p65 Proteine

Struntz, Harki: "Catch and Release DNA Decoys: Capture and Photochemical Dissociation of NF-κB Transcription Factors." in: ACS chemical biology, Vol. 11, Issue 6, pp. 1631-8, (2017) (PubMed).

Shree, Singh, Saxena, Kumar, Agarwal, Sharma, Srivastava, Srivastava, Sanyal, Ramachandran: "The M. tuberculosis HAD phosphatase (Rv3042c) interacts with host proteins and is inhibited by Clofazimine." in: Cellular and molecular life sciences : CMLS, Vol. 73, Issue 17, pp. 3401-17, (2016) (PubMed).

Srinivasan, Blackburn, Lahiri: "Functional characterization of a competitive peptide antagonist of p65 in human macrophage-like cells suggests therapeutic potential for chronic inflammation." in: Drug design, development and therapy, Vol. 8, pp. 2409-21, (2015) (PubMed).

Pereira, Hugo, Malaterre, Huiling, Sonza, Cures, Purcell, Ramsland, Gerondakis, Gonda, Ramsay: "MYB elongation is regulated by the nucleic acid binding of NFκB p50 to the intronic stem-loop region." in: PLoS ONE, Vol. 10, Issue 4, pp. e0122919, (2015) (PubMed).

Thompson, Larson, Vidrine, Barrios, Navarro, Meyers, Simms, Prajapati, Chitsike, Hellman, Baker, Watkins: "FOXO3-NF-κB RelA Protein Complexes Reduce Proinflammatory Cell Signaling and Function." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 12, pp. 5637-47, (2015) (PubMed).

Guo, Lu, Huang, Wu, Zhang, Yu, Zhang, Bao, He, Chen, Jia: "Protective role of PGC-1α in diabetic nephropathy is associated with the inhibition of ROS through mitochondrial dynamic remodeling." in: PLoS ONE, Vol. 10, Issue 4, pp. e0125176, (2015) (PubMed).

Wang, Zhang, Li, Tang, Siedlak, Fujioka, Liu, Su, Pi, Wang: "MFN2 couples glutamate excitotoxicity and mitochondrial dysfunction in motor neurons." in: The Journal of biological chemistry, Vol. 290, Issue 1, pp. 168-82, (2015) (PubMed).

Henkels, Mallets, Dennis, Gomez-Cambronero: "S6K is a morphogenic protein with a mechanism involving Filamin-A phosphorylation and phosphatidic acid binding." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 4, pp. 1299-313, (2015) (PubMed).

Chen, Zhang, Chen, Li, Wu, Deng, Jiao, Li, Ji, Feng, Zeng, Jiang, Zhu: "ATM-mediated PTEN phosphorylation promotes PTEN nuclear translocation and autophagy in response to DNA-damaging agents in cancer cells." in: Autophagy, Vol. 11, Issue 2, pp. 239-52, (2015) (PubMed).

Jagdeo, Dufour, Fung, Luo, Kleifeld, Overall, Jan: "Heterogeneous Nuclear Ribonucleoprotein M Facilitates Enterovirus Infection." in: Journal of virology, Vol. 89, Issue 14, pp. 7064-78, (2015) (PubMed).

Aliase für NF-kB p65 Proteine

REL proto-oncogene, NF-kB subunit (REL) Proteine
RELA proto-oncogene, NF-kB subunit (RELA) Proteine
RELA proto-oncogene, NF-kB subunit (Rela) Proteine
v-rel reticuloendotheliosis viral oncogene homolog A (avian) (Rela) Proteine
REL proto-oncogene, NF-kB subunit (Rel) Proteine
v-rel avian reticuloendotheliosis viral oncogene homolog (rel) Proteine
v-rel avian reticuloendotheliosis viral oncogene homolog L homeolog (rel.L) Proteine
C-Rel Proteine
c-rel Proteine
NFkB Proteine
NFKB3 Proteine
p65 Proteine
rel Proteine
rel-A Proteine
rel2 Proteine
rel3 Proteine
v-rel Proteine
xrel Proteine
Xrel2 Proteine
Xrel3 Proteine
zgc:100833 Proteine
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