Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Select your species
Thus, we concluded that fine-tuning expression of Bcl-3 is needed for proper CD4 (zeige CD4 ELISA Kits)(+) T-cell development and is required to sustain Th17-cell mediated pathology.
Bcl-3 suppressed colorectal tumor formation: Bcl-3-deficient mice were relatively protected from DSS (zeige PMP22 ELISA Kits)-induced epithelial damage and developed more polyps after AOM (zeige COL2A1 ELISA Kits)/DSS (zeige PMP22 ELISA Kits) treatment, although polyp size was unaffected.
this study implicates the intracellular protein (zeige CKAP2 ELISA Kits), BCL3, as a key mediator of the IL-10 (zeige IL10 ELISA Kits)-induced immunosuppressive macrophage phenotype
These results establish that Bcl3 positively regulates pluripotency genes and thus shed light on the mechanism of Bcl3 as a downstream molecule of LIF (zeige LIF ELISA Kits)/STAT3 (zeige STAT3 ELISA Kits) signaling in pluripotency maintenance.
Bcl3 reduces the inflammatory response in pancreas/biliary tissue by blocking ubiquitination and proteasome-mediated degradation of nuclear factor-kappaB p50 (zeige NFKB1 ELISA Kits) homodimers.
Low expression of IL-6 (zeige IL6 ELISA Kits) and TNF-alpha (zeige TNF ELISA Kits) correlates with the presence of the nuclear regulators of NF-kappaB (zeige NFKB1 ELISA Kits), IkappaBNS and BCL-3, in the uterus of mice.
These findings demonstrate that Bcl-3 is required in dendritic cells to prime protective T-cell-mediated immunity to T. gondii
data show that BCL-3 makes extensive contacts with p50 (zeige LSP1 ELISA Kits) homodimers and in particular with ankyrin repeats (ANK) 1 (zeige ANK1 ELISA Kits), 6, and 7, and the N-terminal region of Bcl-3.
The presence of a p50 (zeige LSP1 ELISA Kits)/Bcl-3 complex in nuclear extracts from cells of metastatic lung tissues.
In SOD1 (zeige SOD1 ELISA Kits) and Neurotomized mice the results of this studysuggest LC3 (zeige MAP1LC3A ELISA Kits), Fn14 (zeige TNFRSF12A ELISA Kits), Bcl3 and Gadd45a (zeige GADD45A ELISA Kits) as candidate genes involved in the maintenance of the severe atrophic state.
Akt2 (zeige AKT2 ELISA Kits), Erk2 (zeige MAPK1 ELISA Kits), and IKK1 (zeige CHUK ELISA Kits)/2 phosphorylate Bcl3, converting Bcl3 into a transcriptional coregulator by facilitating its recruitment to DNA.
Bcl-3 knockdown enhanced the degradation of Smad3 (zeige SMAD3 ELISA Kits) but not Smad2 (zeige SMAD2 ELISA Kits) following TGFbeta (zeige TGFB1 ELISA Kits) treatment.
We have shown for the first time that BCL-3 promotes the growth of colorectal cancer cells through activation of the AKT (zeige AKT1 ELISA Kits) pathway, increasing tumour cell yield both in vitro and in vivo.
BCL3 serves as an oncogene (zeige RAB1A ELISA Kits) in glioma by modulating proliferation, cell cycle progression and apoptosis, and its oncogenic effects are mediated by the STAT3 (zeige STAT3 ELISA Kits) signaling pathway.
miR (zeige MLXIP ELISA Kits)-19b silencing promoted cell proliferation and cell cycle progression in gastric cancer cells and BCL3 was identified as a direct target of miR (zeige MLXIP ELISA Kits)-19b
Study confirmed that BCL-3 is overexpressed in hepatocellular carcinoma (HCC (zeige FAM126A ELISA Kits)) tissues and correlated with adverse clinicopathological features and poorer prognosis. BCL-3 can promote the growth of HCC (zeige FAM126A ELISA Kits) cells by promoting cell viability, proliferation and cell cycle progression through regulation of CCND1 (zeige CCND1 ELISA Kits) expression.
Variant of BCL3 gene is strongly associated with five-year survival of non-small-cell lung cancer patients
Subcellular localization of Bcl-3 could be a potential-early diagnostic marker in colon cancer.
Bcl-3 is involved in the development of Tfh cells and the pathogenesis of RA, presumably by inducing IL-21 (zeige IL17C ELISA Kits) production.
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
B-cell CLL/lymphoma 3
, B-cell leukemia/lymphoma 3
, B-cell lymphoma 3 protein homolog
, B-cell lymphoma 3 protein
, B-cell lymphoma 3-encoded protein
, chronic lymphatic leukemia protein
, proto-oncogene BCL3