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Neurofibromin 1 Produkte

(Neurofibromin 1 (NF1))
This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte Neurofibromin 1 Kategorien

Neurofibromin 1 Antikörper

High quality antibodies with extensive validation data.

Neurofibromin 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Neurofibromin 1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Neurofibromin 1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Cow, Dog, Human, Mouse, Rat
Applikation ELISA, WB, IP, DB
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN540944
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IF, IHC (p), EIA
Validierungen
  • (4)
Kat. Nr. ABIN953662
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IF, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7161270
Menge 100 μg
Datenblatt Datenblatt

Empfohlene Neurofibromin 1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968859
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1144677
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Chicken
Analytical Method
Validierungen
Kat. Nr. ABIN1144674
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Neurofibromin 1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN1312428
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124148
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3094141
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Neurofibromin 1 Produkten

Miwa, Inoue, Sakamoto: "MRG-1 is required for both chromatin-based transcriptional silencing and genomic integrity of primordial germ cells in Caenorhabditis elegans." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 24, Issue 5, pp. 377-389, (2019) (PubMed).

Yoshioka, Gros, Li, Kumar, Deacon, Maron, Muotri, Chi, Fu, Yu, Dowdy: "Efficient generation of human iPSCs by a synthetic self-replicative RNA." in: Cell stem cell, Vol. 13, Issue 2, pp. 246-54, (2013) (PubMed).

Wallace, Pfefferle, Shen, McNairn, Cerami, Fallon, Rinaldi, Southard, Perou, Schimenti: "Comparative oncogenomics implicates the neurofibromin 1 gene (NF1) as a breast cancer driver." in: Genetics, Vol. 192, Issue 2, pp. 385-96, (2012) (PubMed).

Tucker, Riccardi, Brown, Fee, Sutcliffe, Vielkind, Wechsler, Wolkenstein, Friedman: "S100B and neurofibromin immunostaining and X-inactivation patterns of laser-microdissected cells indicate a multicellular origin of some NF1-associated neurofibromas." in: Journal of neuroscience research, Vol. 89, Issue 9, pp. 1451-60, (2011) (PubMed).

Kweh, Zheng, Kurenova, Wallace, Golubovskaya, Cance: "Neurofibromin physically interacts with the N-terminal domain of focal adhesion kinase." in: Molecular carcinogenesis, Vol. 48, Issue 11, pp. 1005-17, (2009) (PubMed).

Sales, Engelmayr, Johnson, Gao, Wang, Sacks, Mayer et al.: "Protein precoating of elastomeric tissue-engineering scaffolds increased cellularity, enhanced extracellular matrix protein production, and differentially regulated the phenotypes of circulating ..." in: Circulation, Vol. 116, Issue 11 Suppl, pp. I55-63, (2007) (PubMed).

Kuorilehto, Ekholm, Nissinen, Hietaniemi, Hiltunen, Paavolainen, Penttinen, Peltonen: "NF1 gene expression in mouse fracture healing and in experimental rat pseudarthrosis." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 54, Issue 3, pp. 363-70, (2006) (PubMed).

Hisaoka, Hashimoto, Ohguri, Aoki, Okamoto, Tanaka, Okimoto, Nakamura, Ishida: "Congenital (infantile) pseudarthrosis of the fibula associated with osteofibrous dysplasia." in: Skeletal radiology, Vol. 33, Issue 9, pp. 545-9, (2004) (PubMed).

Zou, Butcher, Sadikovic, Groves, Yee, Rodenhiser: "Characterization of functional elements in the neurofibromatosis (NF1) proximal promoter region." in: Oncogene, Vol. 23, Issue 2, pp. 330-9, (2004) (PubMed).

Zhu, Saberwal, Lu, Platanias, Eklund: "The interferon consensus sequence-binding protein activates transcription of the gene encoding neurofibromin 1." in: The Journal of biological chemistry, Vol. 279, Issue 49, pp. 50874-85, (2004) (PubMed).

Synonyme und alternative Namen zu Neurofibromin 1

neurofibromin 1 (NF1), neurofibromin 1 (Nf1), Neurofibromin 1 (Nf1), neurofibromin 1a (nf1a), neurofibromin (LOC593418), neurofibromin (LOC5570549), neurofibromin (CpipJ_CPIJ011774), putative neurofibromin (Smp_148460), AW494271, CG8318, Dmel\\CG8318, dNF1, E030030H24Rik, fe06d03, hm:zehn0874, NF-1, Nf-1, NF1, nf1, NFNS, VRNF, WSS, wu:fe06d03, zehn0874

Bezeichner auf Proteinebene für Neurofibromin 1

  • neurofibromatosis-related protein NF-1
  • neurofibromin
  • Neurofibromatosis type 1
  • neurofibromatosis 1
  • CG8318-PB
  • CG8318-PC
  • CG8318-PD
  • CG8318-PE
  • CG8318-PF
  • Neurofibromatosis-1
  • Nf1-PB
  • Nf1-PC
  • Nf1-PD
  • Nf1-PE
  • Nf1-PF
  • neurofibramatosis-1
  • neurofibromatosis factor 1
  • neurofibromatosis type 1
  • neurofibromin 1
  • neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease)
  • neurofibromin-like
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