NCOR2 Produkte
(Nuclear Receptor Co-Repressor 2 (NCOR2))
Kategorien
This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Apr 2011].
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Ausgewählte NCOR2 Kategorien
NCOR2 Antikörper
High quality antibodies with extensive validation data.
NCOR2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Empfohlene NCOR2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN6144422
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validierungen
- (2)
Kat. Nr.
ABIN686302
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN564153
Menge
50 μL
Datenblatt
Datenblatt
Empfohlene NCOR2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969004
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969005
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative DNA-Binding ELISA
Validierungen
Kat. Nr.
ABIN5648559
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NCOR2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1312140
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NCOR2 Produkten
: "SpliceArray profiling of breast cancer reveals a novel variant of NCOR2/SMRT that is associated with tamoxifen resistance and control of ER? transcriptional activity." in: Cancer research, Vol. 73, Issue 1, pp. 246-55, (2013) (PubMed).: "miR-16 targets transcriptional corepressor SMRT and modulates NF-kappaB-regulated transactivation of interleukin-8 gene." in: PLoS ONE, Vol. 7, Issue 1, pp. e30772, (2012) (PubMed).
: "In vivo and in vitro evidence that PPARγ ligands are antagonists of leptin signaling in breast cancer." in: The American journal of pathology, Vol. 179, Issue 2, pp. 1030-40, (2011) (PubMed).
: "Regulation of androgen receptor activity by the nuclear receptor corepressor SMRT." in: The Journal of biological chemistry, Vol. 278, Issue 7, pp. 5052-61, (2003) (PubMed).
: "Repressors of androgen and progesterone receptor action." in: The Journal of biological chemistry, Vol. 278, Issue 33, pp. 31136-48, (2003) (PubMed).
: "SMRTE inhibits MEF2C transcriptional activation by targeting HDAC4 and 5 to nuclear domains." in: The Journal of biological chemistry, Vol. 276, Issue 26, pp. 24177-85, (2001) (PubMed).
: "Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway." in: Genes & development, Vol. 14, Issue 1, pp. 45-54, (2000) (PubMed).
: "Unique forms of human and mouse nuclear receptor corepressor SMRT." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 6, pp. 2639-44, (1999) (PubMed).
: "The nuclear corepressors NCoR and SMRT are key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor." in: Molecular and cellular biology, Vol. 18, Issue 3, pp. 1369-78, (1998) (PubMed).
: "Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase." in: Cell, Vol. 89, Issue 3, pp. 373-80, (1997) (PubMed).
Synonyme und alternative Namen zu NCOR2
nuclear receptor corepressor 2 (NCOR2), nuclear receptor co-repressor 2 (Ncor2), nuclear receptor corepressor 2 (ncor2), nuclear receptor co-repressor 2 (NCOR2), CTG26, ctg26, gb:be017685, N-CoR, N-CoR2, NCOR2, si:bz71m17.2, SMAP270, SMRT, smrt, SMRTE, SMRTe, smrte, SMRTE-tau, smrte-tau, TNRC14, tnrc14, TRAC, TRAC-1, trac-1, TRAC1, trac1Bezeichner auf Proteinebene für NCOR2
- CTG repeat protein 26
- T3 receptor-associating factor
- silencing mediator for retinoid and thyroid hormone receptors
- thyroid-, retinoic-acid-receptor-associated corepressor
- nuclear receptor corepressor 2
- nuclear receptor co-repressor 2
- N-CoR2
- TRAC
- silencing mediator of retinoic acid and thyroid hormone receptor
- silencing mediator of retinoid acid and thyroid hormone receptor
- silencing mediator
- thyroid hormone receptor
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