N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Produkte
(N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))
Kategorien
This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Kategorien
N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Antikörper
High quality antibodies with extensive validation data.
N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7434806
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN513533
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN7142987
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6958012
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124089
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345780
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7575014
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 Produkten
: "A Guanidine-Based Synthetic Compound Suppresses Angiogenesis via Inhibition of Acid Ceramidase." in: ACS chemical biology, Vol. 14, Issue 1, pp. 11-19, (2019) (PubMed).: "The investigation of ceranib-2 on apoptosis and drug interaction with carboplatin in human non small cell lung cancer cells in vitro." in: Cytotechnology, Vol. 70, Issue 1, pp. 387-396, (2018) (PubMed).
: "Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION." in: The Journal of biological chemistry, Vol. 291, Issue 5, pp. 2422-34, (2016) (PubMed).
: "Acid ceramidase is upregulated in AML and represents a novel therapeutic target." in: Oncotarget, Vol. 7, Issue 50, pp. 83208-83222, (2016) (PubMed).
: "Quantitative proteomics analysis using 2D-PAGE to investigate the effects of cigarette smoke and aerosol of a prototypic modified risk tobacco product on the lung proteome in C57BL/6 mice." in: Journal of proteomics, Vol. 145, pp. 237-45, (2016) (PubMed).
: "Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells." in: Biochimica et biophysica acta, Vol. 1841, Issue 4, pp. 552-62, (2014) (PubMed).
: "Ceramide biosynthesis and metabolism in trophoblast syncytialization." in: Molecular and cellular endocrinology, Vol. 362, Issue 1-2, pp. 48-59, (2012) (PubMed).
: "Acid ceramidase (ASAH1) is a global regulator of steroidogenic capacity and adrenocortical gene expression." in: Molecular endocrinology (Baltimore, Md.), Vol. 26, Issue 2, pp. 228-43, (2012) (PubMed).
: "Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor." in: Molecular and cellular biology, Vol. 32, Issue 21, pp. 4419-31, (2012) (PubMed).
: "Clinical utility of serum autoantibodies detected by protein microarray in melanoma." in: International journal of proteomics, Vol. 2011, pp. 413742, (2011) (PubMed).
Synonyme und alternative Namen zu N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1
N-acylsphingosine amidohydrolase 1 (ASAH1), N-acylsphingosine amidohydrolase 1 (Asah1), N-acylsphingosine amidohydrolase (acid ceramidase) 1 (ASAH1), N-acylsphingosine amidohydrolase (acid ceramidase) 1 L homeolog (asah1.L), N-acylsphingosine amidohydrolase (acid ceramidase) 1a (asah1a), Acid ceramidase (asah-1), N-acylsphingosine amidohydrolase (acid ceramidase) 1b (asah1b), 2310081N20Rik, AC, ACDase, ASAH, Asah, asah1, ASAH1, MGC82286, PHP, PHP32, SMAPME, zgc:66026, zgc:101637Bezeichner auf Proteinebene für N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1
- acid CDase
- acid ceramidase
- acylsphingosine deacylase
- putative 32 kDa heart protein
- ACDase
- Acylsphingosine deacylase
- N-acylsphingosine amidohydrolase 1
- AC
- N-acylsphingosine amidohydrolase (acid ceramidase) 1
- N-acylsphingosine amidohydrolase
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