anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) Antikörper

Bezeichnung:: anti-Polycystic Kidney Disease 1 (Autosomal Dominant) Antikörper (PKD1)

Auf www.antikoerper-online.de finden Sie aktuell 60 Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) Antikörper von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Polycystic Kidney Disease 1 (Autosomal Dominant) Kits (7) und Polycystic Kidney Disease 1 (Autosomal Dominant) Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 73 Polycystic Kidney Disease 1 (Autosomal Dominant) Produkte verfügbar.

Synonyme:: mFLJ00285, PBP, Pc-1, PC1, TRPP1

Alle Antikörper anzeigen	Gen	GeneID	UniProt
	PKD1	5310	P98161
	PKD1	18763	O08852
	PKD1	24650
Alle Spezies anzeigen Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) Antikörper

Wählen Sie die Spezies und Applikation aus

anti-Human Antikörper:

anti-Mouse (Murine) Antikörper:

anti-Rat (Rattus) Antikörper:

Alle verfügbaren anti-Polycystic Kidney Disease 1 (Autosomal Dominant) Antikörper

Sie gelangen zu unserer vorgefilterten Suche.

Verknüpfte Pathways mit anti-Polycystic Kidney Disease 1 (Autosomal Dominant) Antikörper

Weitere Produktkategorien zu Polycystic Kidney Disease 1 (Autosomal Dominant) Antikörper

Am meisten referenzierte anti-Polycystic Kidney Disease 1 (Autosomal Dominant) Antikörper

Human Polyclonal PKD1 Primary Antibody für IF (p), IHC (p) - ABIN678083 : Chiou, Sang, Cheng, Ho, Wang, Pan: Peracetylated (-)-epigallocatechin-3-gallate (AcEGCG) potently prevents skin carcinogenesis by suppressing the PKD1-dependent signaling pathway in CD34+ skin stem cells and skin tumors. in Carcinogenesis 2013 (PubMed)
Show all 4 Pubmed References

Weitere Antikörper gegen Polycystic Kidney Disease 1 (Autosomal Dominant) Interaktionspartner

Human Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) Interaktionspartner

These data reveal a novel function for PKD1 as a regulator of focal adhesion dynamics and by identifying PIP5Klgamma as a novel PKD1 substrate provide mechanistic insight into this process.
the PKD1/PKD2 (zeige PKD2 Antikörper) mutation status differed by ethnicity, and the PKD1/PKD2 (zeige PKD2 Antikörper) genotype may affect the clinical phenotype of autosomal dominant polycystic kidney disease
The novel pathogenic variants c.3607C> T and c.11354G> C in PKD1 is very interesting since they may represent Italian clusters.
SNX3 (zeige SNX3 Antikörper)-retromer complex regulates the surface expression and function of PC1 (zeige PCSK1 Antikörper) and PC2 (zeige KRT6B Antikörper)
Study identified a novel heterozygous frameshift mutation in PKD1 gene segregating between affected and unaffected individuals suggesting an involvement in polycystic kidney disease (PKD (zeige PRKD1 Antikörper)).
we report for the first time that PKD1 was tightly regulated by androgen at the transcriptional level in prostate cancer cells and was a novel androgen-repressed gene. Further analysis identified FRS2 (zeige FRS2 Antikörper) as a novel mediator of androgen-induced PKD1 repression.
Hyperactivation of the ERK (zeige EPHB2 Antikörper) pathway may be caused by down-regulation of PC-1 (zeige PCSK1 Antikörper) and PC-2 (zeige KRT6B Antikörper) in lymphatic malformations, contributing to increased proliferation of lymphatic endothelial cells.
A novel mutation of the PKD1 gene has been identified with autosomal dominant polycystic kidney disease in an affected Chinese family.
Annualized median liver growth rates were 1.68, 1.5 and 1.24% for PKD1-T, PKD1-NT and PKD2 (zeige PKD2 Antikörper) mutations, respectively (P = 0.49), and remained unaffected by the ADPKD genotype when adjusted for age, gender and baseline HtLV.
this study shows that diet-induced obesity links to estrogen receptor (zeige ESR1 Antikörper)-positive breast cancer progression via LPA (zeige APOA Antikörper)/PKD-1-CD36 (zeige CD36 Antikörper) signaling-mediated microvascular remodeling

Mouse (Murine) Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) Interaktionspartner

PC1/3 (zeige PCSK1 Antikörper) deficiency was associated with increased expression of melanocortin receptors and PRCP (prolylcarboxypeptidase (zeige PRCP Antikörper), a catabolic enzyme for alpha-melanocyte stimulating hormone (alphaMSH (zeige POMC Antikörper))), and reduced adrenocorticotropic hormone secretion. We conclude that the obesity accompanying PCSK1 (zeige PCSK1 Antikörper) deficiency may not be primarily due to alphaMSH (zeige POMC Antikörper) deficiency.
Mutations in PKD1 is associated with autosomal dominant polycystic kidney disease.
critical functions of PC1 are regulated by its ability to sense cytosolic calcium levels via binding to calmodulin
cortactin (zeige CTTN Antikörper) binds to E-cadherin (zeige CDH1 Antikörper), and that a posttranslational modification of cortactin (zeige CTTN Antikörper), RhoA (zeige RHOA Antikörper)-induced phosphorylation by protein kinase D1 (PKD1; also known as PRKD1 (zeige PRKD1 Antikörper)) at S298, impairs adherens junction assembly and supports their dissolution.
Galpha12 (zeige GNA12 Antikörper) is required for the development of kidney cysts induced by Pkd1 mutation in mouse autosomal dominant polycystic kidney disease.
PAK-mediated phosphorylation of PKD1 at Ser203 triggers its membrane dissociation and subsequent entry into the nucleus, thereby regulating the phosphorylation of PKD1 nuclear targets, including class IIa histone deacetylases.
kd1 mutant mice have transcriptional profiles consistent with changes in lipid metabolism and distinct metabolite and complex lipid profiles in kidneys. .. cells lacking Pkd1 have an intrinsic fatty acid oxidation defect and that manipulation of lipid content of mouse chow modifies cystic disease.
Polycystin 1 was overexpressed in M1 cells, no increase in any of these parameters was detected
detected a marked increase in the localization of beta-catenin (zeige CTNNB1 Antikörper) in the nucleus of crypt epithelial cells in the ileum of PKD1
PKD1 phosphorylates AMPKalpha2 (zeige PRKAA2 Antikörper) at Ser485/491, thus diminishing AMPK (zeige PRKAA1 Antikörper) activity.

Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the polycystin protein family. The encoded glycoprotein contains a large N-terminal extracellular region, multiple transmembrane domains and a cytoplasmic C-tail. It is an integral membrane protein that functions as a regulator of calcium permeable cation channels and intracellular calcium homoeostasis. It is also involved in cell-cell/matrix interactions and may modulate G-protein-coupled signal-transduction pathways. It plays a role in renal tubular development, and mutations in this gene cause autosomal dominant polycystic kidney disease type 1 (ADPKD1). ADPKD1 is characterized by the growth of fluid-filled cysts that replace normal renal tissue and result in end-stage renal failure. Splice variants encoding different isoforms have been noted for this gene. Also, six pseudogenes, closely linked in a known duplicated region on chromosome 16p, have been described.

Alternative names and synonyms associated with Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)

polycystin 1, transient receptor potential channel interacting (PKD1) Antikörper
polycystin 1, transient receptor poteintial channel interacting (Pkd1) Antikörper
polycystin 1, transient receptor potential channel interacting (Pkd1) Antikörper
polycystin-1 (LOC749291) Antikörper

mFLJ00285 Antikörper
PBP Antikörper
Pc-1 Antikörper
PC1 Antikörper
TRPP1 Antikörper

Bezeichner auf Proteinebene für PKD1

autosomal dominant polycystic kidney disease 1 protein , polycystic kidney disease-associated protein , polycystin 1 , polycystin-1 , transient receptor potential cation channel, subfamily P, member 1 , autosomal dominant polycystic kidney disease 1 protein homolog , polycystic kidney disease 1 homolog; polycystin-1 , polycystic kidney disease 1 (autosomal dominant) , polycystic kidney disease protein 1

GENE ID	SPEZIES
5310	Homo sapiens
18763	Mus musculus
24650	Rattus norvegicus
416553	Gallus gallus
749291	Pan troglodytes
606755	Canis lupus familiaris
100516429	Sus scrofa

Ausgewählte Anbieter für anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) Antikörper

Haben Sie etwas anderes gesucht?

Telefon:	+1 877 302 8632
Fax:	+1 888 205 9894 (Toll-free)
E-Mail:	orders@antikoerper-online.de

Show all anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) Antikörper with Pubmed References

Human Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) Interaktionspartner

Mouse (Murine) Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) Interaktionspartner

Beschreibung des Gens

Alternative names and synonyms associated with Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1)

Bezeichner auf Proteinebene für PKD1