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Results indicated that sine oculis homeobox 1 (Six1) overexpression could significantly promote the expression of fast-type muscle genes Atp2a1, Srl, and Mylpf.
Therefore, we suggest that Chr 21 gene(s) distal from the ETS2 locus reduce mouse mlc2a and PEBP expression in DS model mice and DS.
RLC-f is necessary for skeletal muscle formation. The lack of skeletal muscle formation observed in RLC-f null mice indicates the total dependence of skeletal muscle development on the presence of RLC-f during embryogenesis.
Data suggest that the overexpression of fast skeletal muscle myosin light chain in murine asthma may be associated with the changes of bronchial smooth muscle.
A cDNA clone encoding human fast skeletal myosin regulatory light chain (HSRLC) has been isolated and characterized from a fetal muscle cDNA library.
The subcellular localization, the temporal and spatial distributions and the association between the presence of specific polymorphisms and commercial meat traits of the porcine fast myosin regulatory light chain gene (HUMMLC2B) in muscle, was examined.
Since we know so little about the molecules regulating vertebrate myocyte fusion, we propose that the mylpfa:H2B-GFP transgene will be a very useful reporter for conducting forward and reverse genetic screens to identify new components regulating vertebrate myocyte fusion.
Data show a novel interaction between zebrafish Nanos and myosin light chain II (Mylz2).
mlc-2 gene is expressed in atrial and ventricular cardiomyocytes during early embryonic development, but also in the adult heart; cardiac MLC-2 is required for thick-filament stabilization and contractility in the vertebrate heart
Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
, fast skeletal myosin light chain 2
, myosin light chain 2
, myosin regulatory light chain 2, skeletal muscle isoform
, Myosin light polypeptide 2 alkali
, Myosin, light polypeptide 2, alkali
, Myosin, light polypeptide 2, alkali; ventricular, skeletal, slow
, ventricular skeletal slow
, ventricular, skeletal, slow
, myosin, light chain 11, regulatory
, myosin light chain, phosphorylatable, fast skeletal muscle
, myosin light chain type 2
, skeletal muscle isoform
, myosin regulatory light chain 2, skeletal muscle isoform type 2
, Myosin regulatory light chain 2, skeletal muscle isoform type 1
, myosin light chain phosphorylatable fast skeletal muscle protein
, myosin regulatory light chain 2
, skeletal muscle myosin regulatory light chain 2
, phosphorylatable fast skeletal muscle myosin light chain
, myosin, light polypeptide 2, skeletal muscle