MYLK Produkte
(Myosin Light Chain Kinase (MYLK))
Kategorien
This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008].
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Ausgewählte MYLK Kategorien
MYLK Antikörper
High quality antibodies with extensive validation data.
MYLK ELISA Kits
Reliable ELISA kits for a wide range of species.
MYLK Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MYLK Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC, ICC, FACS
Validierungen
- (9)
Kat. Nr.
ABIN7193606
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, ICC, IP
Validierungen
- (5)
Kat. Nr.
ABIN7439105
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB
Validierungen
- (2)
- (4)
Kat. Nr.
ABIN392495
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene MYLK ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968752
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968751
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957977
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MYLK Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf21)
Validierungen
- (2)
Kat. Nr.
ABIN5569798
Menge
5 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1311785
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1311787
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MYLK Produkten
: "The Protective Effect of Radix Polygoni Multiflori on Diabetic Encephalopathy via Regulating Myosin Light Chain Kinase Expression." in: Journal of diabetes research, Vol. 2015, pp. 484721, (2016) (PubMed).: "Interferon Stimulated Gene 15 upregulation precedes the development of blood brain barrier disruption and cerebral edema after traumatic brain injury in young mice." in: Journal of neurotrauma, (2015) (PubMed).
: "Pseudomonas fluorescens alters the intestinal barrier function by modulating IL-1? expression through hematopoietic NOD2 signaling." in: Inflammatory bowel diseases, Vol. 21, Issue 3, pp. 543-55, (2015) (PubMed).
: "P2Y6 Receptor-Mediated Microglial Phagocytosis in Radiation-Induced Brain Injury." in: Molecular neurobiology, (2015) (PubMed).
: "Yersinia pseudotuberculosis disrupts intestinal barrier integrity through hematopoietic TLR-2 signaling." in: The Journal of clinical investigation, Vol. 122, Issue 6, pp. 2239-51, (2012) (PubMed).
: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).
: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).
: "The RET proto-oncogene in human cancers." in: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).
: "Analysis of the kinase-related protein gene found at human chromosome 3q21 in a multi-gene cluster: organization, expression, alternative splicing, and polymorphic marker." in: Journal of cellular biochemistry, Vol. 75, Issue 3, pp. 481-91, (2000) (PubMed).
Synonyme und alternative Namen zu MYLK
myosin light chain kinase (MYLK), myosin light chain kinase (Mylk), myosin, light polypeptide kinase (Mylk), myosin, light chain kinase a (mylka), 9530072E15Rik, A930019C19Rik, AAT7, AW489456, fj60a06, KRP, MLCK, Mlck, mlck, MLCK1, mlck1a, MLCK108, MLCK210, MSTP083, mylk, MYLK1, smMLCK, SMMLCK, wu:fj60a06, zmlck1Bezeichner auf Proteinebene für MYLK
- kinase-related protein
- myosin light chain kinase, smooth muscle
- myosin, light polypeptide kinase
- smooth muscle myosin light chain kinase
- telokin
- kinase related protein, telokin
- myosin, light chain kinase
- MLCK
- myosin light chain kinase
- myosin light chain kinase, smooth muscle-like
- smooth muscle myosin light chain kinase (61-kDa active fragment)
- myosin light chain kinase 1
- smooth muscle MLCK
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