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MYLK Produkte

(Myosin Light Chain Kinase (MYLK))

Kategorien

This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008].

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Ausgewählte MYLK Kategorien

MYLK Antikörper

High quality antibodies with extensive validation data.

MYLK ELISA Kits

Reliable ELISA kits for a wide range of species.

MYLK Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MYLK Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation ELISA, IHC, WB
Validierungen
  • (7)
Kat. Nr. ABIN5693029
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation IHC, ELISA, WB
Validierungen
  • (5)
Kat. Nr. ABIN3031918
Menge 0.4 mL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation ELISA, WB
Validierungen
  • (3)
Kat. Nr. ABIN6263474
Menge 100 μL
Datenblatt Datenblatt

Empfohlene MYLK ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968751
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6968752
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6957977
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MYLK Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (2)
Kat. Nr. ABIN5569798
Menge 5 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1311784
Menge 2 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1311785
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MYLK Produkten

He, Wang, Chen, Liu, Pan, Li: "The Protective Effect of Radix Polygoni Multiflori on Diabetic Encephalopathy via Regulating Myosin Light Chain Kinase Expression." in: Journal of diabetes research, Vol. 2015, pp. 484721, (2016) (PubMed).

Rossi, Todd, Daniels, Bazan, Belayev: "Interferon Stimulated Gene 15 upregulation precedes the development of blood brain barrier disruption and cerebral edema after traumatic brain injury in young mice." in: Journal of neurotrauma, (2015) (PubMed).

Alnabhani, Montcuquet, Biaggini, Dussaillant, Roy, Ogier-Denis, Madi, Jallane, Feuilloley, Hugot, Connil, Barreau: "Pseudomonas fluorescens alters the intestinal barrier function by modulating IL-1? expression through hematopoietic NOD2 signaling." in: Inflammatory bowel diseases, Vol. 21, Issue 3, pp. 543-55, (2015) (PubMed).

Xu, Hu, Liu, Xu, Li, Wu, Shi, Tang: "P2Y6 Receptor-Mediated Microglial Phagocytosis in Radiation-Induced Brain Injury." in: Molecular neurobiology, (2015) (PubMed).

Jung, Meinzer, Montcuquet, Thachil, Château, Thiébaut, Roy, Alnabhani, Berrebi, Dussaillant, Pedruzzi, Thenet, Cerf-Bensussan, Hugot, Barreau: "Yersinia pseudotuberculosis disrupts intestinal barrier integrity through hematopoietic TLR-2 signaling." in: The Journal of clinical investigation, Vol. 122, Issue 6, pp. 2239-51, (2012) (PubMed).

Cantrell: "Phosphoinositide 3-kinase signalling pathways." in: Journal of cell science, Vol. 114, Issue Pt 8, pp. 1439-45, (2001) (PubMed).

Blume-Jensen, Hunter: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, (2001) (PubMed).

Jhiang: "The RET proto-oncogene in human cancers." in: Oncogene, Vol. 19, Issue 49, pp. 5590-7, (2000) (PubMed).

Watterson, Schavocky, Guo, Weiss, Chlenski, Shirinsky, Van Eldik, Haiech: "Analysis of the kinase-related protein gene found at human chromosome 3q21 in a multi-gene cluster: organization, expression, alternative splicing, and polymorphic marker." in: Journal of cellular biochemistry, Vol. 75, Issue 3, pp. 481-91, (2000) (PubMed).

Synonyme und alternative Namen zu MYLK

myosin light chain kinase (MYLK), myosin light chain kinase (Mylk), myosin, light polypeptide kinase (Mylk), myosin, light chain kinase a (mylka), 9530072E15Rik, A930019C19Rik, AAT7, AW489456, fj60a06, KRP, MLCK, Mlck, mlck, MLCK1, mlck1a, MLCK108, MLCK210, MSTP083, mylk, MYLK1, smMLCK, SMMLCK, wu:fj60a06, zmlck1

Bezeichner auf Proteinebene für MYLK

  • kinase-related protein
  • myosin light chain kinase, smooth muscle
  • myosin, light polypeptide kinase
  • smooth muscle myosin light chain kinase
  • telokin
  • kinase related protein, telokin
  • myosin, light chain kinase
  • MLCK
  • myosin light chain kinase
  • myosin light chain kinase, smooth muscle-like
  • smooth muscle myosin light chain kinase (61-kDa active fragment)
  • myosin light chain kinase 1
  • smooth muscle MLCK
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