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Myc Tag Produkte

(Myc Tag)

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The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008].

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Empfohlene Myc Tag Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Applikation IP, ELISA, WB
Validierungen
  • (3)
  • (6)
Kat. Nr. ABIN104383
Menge 100 μg
Datenblatt Datenblatt
Reaktivität
Applikation IF, IP, ELISA, WB
Validierungen
  • (9)
  • (3)
Kat. Nr. ABIN962814
Menge 100 μg
Datenblatt Datenblatt
Reaktivität
Applikation ELISA, WB
Validierungen
  • (4)
Kat. Nr. ABIN3028853
Menge 0.4 mL
Datenblatt Datenblatt

Neueste Publikationen zu unseren Myc Tag Produkten

Ferreira, Rosa Soares, Ramalho, Ribeiro-Rodrigues, Máximo, Zuzarte, Girão, Pereira: "Exosomes and STUB1/CHIP cooperate to maintain intracellular proteostasis." in: PLoS ONE, Vol. 14, Issue 10, pp. e0223790, (2020) (PubMed).

Bery, Cruz-Migoni, Bataille, Quevedo, Tulmin, Miller, Russell, Phillips, Carr, Rabbitts: "BRET-based RAS biosensors that show a novel small molecule is an inhibitor of RAS-effector protein-protein interactions." in: eLife, Vol. 7, (2019) (PubMed).

Tanaka, Kaida, Yokoi, Ishii, Nishizawa, Kawamata, Katoh, Sato, Nakamura, Watanabe, Yamashita: "Critical relevance of genomic gains of PRL-3/EGFR/c-myc pathway genes in liver metastasis of colorectal cancer." in: Oncology letters, Vol. 17, Issue 1, pp. 1257-1266, (2019) (PubMed).

Miyamoto, Katayama, Shigematsu, Nishi, Fukuda: "Striosome-based map of the mouse striatum that is conformable to both cortical afferent topography and uneven distributions of dopamine D1 and D2 receptor-expressing cells." in: Brain structure & function, Vol. 223, Issue 9, pp. 4275-4291, (2019) (PubMed).

Gopalakrishnan, Matta, Choi, Natarajan, Prins, Gong, Zenunovic, Narasappa, Patel, Prakash, Chaudhary, Sikri, Chitnis, Kochegarov, Wang, Falat, Kahn, Keerthipati, Sharma, Lenka, Stieben, Braun, Batra et al.: "A novel luciferase-based assay for the detection of Chimeric Antigen Receptors. ..." in: Scientific reports, Vol. 9, Issue 1, pp. 1957, (2019) (PubMed).

Zakiryanova, Kustova, Urazalieva, Baimuchametov, Nakisbekov, Shurin: "Abnormal Expression of c-Myc Oncogene in NK Cells in Patients with Cancer." in: International journal of molecular sciences, Vol. 20, Issue 3, (2019) (PubMed).

Büssow, Themann, Luu, Pentrowski, Harting, Majewski, Vollmer, Köster, Grashoff, Zawatzky, Van den Heuvel, Kröger, Böldicke: "ER intrabody-mediated inhibition of interferon α secretion by mouse macrophages and dendritic cells." in: PLoS ONE, Vol. 14, Issue 4, pp. e0215062, (2019) (PubMed).

Wu, Fan, Ma, Geng: "miR-708-5p promotes fibroblast-like synoviocytes' cell apoptosis and ameliorates rheumatoid arthritis by the inhibition of Wnt3a/β-catenin pathway." in: Drug design, development and therapy, Vol. 12, pp. 3439-3447, (2019) (PubMed).

Jiao, Ahmed, Sim, Bejar, Zhang, Talukder, Rice, Flannick, Podgornaia, Reilly, Engreitz, Kost-Alimova, Hartland, Mercader, Georges, Wagh, Tadin-Strapps, Doench, Edwardson, Rochford, Rosen, Majithia: "Discovering metabolic disease gene interactions by correlated effects on cellular morphology." in: Molecular metabolism, Vol. 24, pp. 108-119, (2019) (PubMed).

Pedrosa, Bodrug, Gomez-Escudero, Carter, Reynolds, Georgiou, Fernandez, Lees, Kostourou, Alexopoulou, Batista, Tavora, Serrels, Parsons, Iskratsch, Hodivala-Dilke: "Tumor angiogenesis is differentially regulated by phosphorylation of endothelial cell focal adhesion kinase tyrosines-397 and -861." in: Cancer research, (2019) (PubMed).

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