MORF4L1 Produkte
(Mortality Factor 4 Like 1 (MORF4L1))
Kategorien
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci (By similarity).
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Ausgewählte MORF4L1 Kategorien
MORF4L1 Antikörper
High quality antibodies with extensive validation data.
MORF4L1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MORF4L1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Pig, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (6)
Kat. Nr.
ABIN185075
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Applikation
WB, IHC
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN2777616
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7239452
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene MORF4L1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6231386
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MORF4L1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7554597
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7563489
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124021
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MORF4L1 Produkten
: "Histone deacetylase 2 (HDAC2) protein-dependent deacetylation of mortality factor 4-like 1 (MORF4L1) protein enhances its homodimerization." in: The Journal of biological chemistry, Vol. 289, Issue 10, pp. 7092-8, (2014) (PubMed).: "KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription." in: The EMBO journal, Vol. 30, Issue 8, pp. 1473-84, (2011) (PubMed).
: "MRG15, a novel chromodomain protein, is present in two distinct multiprotein complexes involved in transcriptional activation." in: The Journal of biological chemistry, Vol. 277, Issue 52, pp. 50860-6, (2002) (PubMed).
Synonyme und alternative Namen zu MORF4L1
mortality factor 4 like 1 (MORF4L1), mortality factor 4 like 1 (Morf4l1), MORF-related gene 15 (MRG15), MRG15 (CpipJ_CPIJ013367), mortality factor 4 like 1 S homeolog (morf4l1.S), mortality factor 4 like 1 (morf4l1), CG6363, Dmel\\CG6363, DmMRG15, Dmrg15, dMRG15, dMrg15, Eaf3, HsT17725, l(3)j6A3, MEAF3, mKIAA4002, MORF4L2, MORFRG15, MRG15, Mrg15, S863-6, TEG-189, Tex189, zgc:92289Bezeichner auf Proteinebene für MORF4L1
- Esa1p-associated factor 3 homolog
- MORF-related gene 15 protein
- MORF-related gene on chromosome 15
- mortality factor 4-like protein 1
- protein MSL3-1
- transcription factor-like protein MRG15
- testis expressed gene 189
- testis-expressed gene 189 protein
- MORF-related gene 15
- mortality factor 4 like 2
- CG6363-PA
- CG6363-PB
- MRG15-PA
- MRG15-PB
- MRG15
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