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MGMT Produkte

(O6-Methylguanine-DNA-Methyltransferase (MGMT))

Kategorien

Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a

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Ausgewählte MGMT Kategorien

MGMT Antikörper

High quality antibodies with extensive validation data.

MGMT ELISA Kits

Reliable ELISA kits for a wide range of species.

MGMT Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MGMT Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, FACS, ICC, IHC, WB
Validierungen
  • (7)
Kat. Nr. ABIN5542437
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Rat
Applikation IF (cc), IF (p), IHC (fro), IHC (p), WB
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN730768
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS, IHC, ELISA, WB
Validierungen
  • (5)
Kat. Nr. ABIN3032088
Menge 0.4 mL
Datenblatt Datenblatt

Empfohlene MGMT ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6958286
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969037
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958287
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MGMT Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3133462
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3083719
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN1047378
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MGMT Produkten

Kotsarenko, Lylo, Ruban, Macewicz, Lukash: "Effects of Some Growth Factors and Cytokines on the Expression of the Repair Enzyme MGMT and Protein MARP in Human Cells In Vitro : Effect of Some Growth Factors and Cytokines." in: Biochemical genetics, Vol. 56, Issue 5, pp. 459-477, (2018) (PubMed).

Koncar, Chu, Romick-Rosendale, Wells, Chan, Qi, Bahassi: "PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas." in: Oncotarget, Vol. 8, Issue 9, pp. 15827-15837, (2017) (PubMed).

Altinoz, Elmaci, Bolukbasi, Ekmekci, Yenmis, Sari, Sav: "MGMT gene variants, temozolomide myelotoxicity and glioma risk. A concise literature survey including an illustrative case." in: Journal of chemotherapy (Florence, Italy), Vol. 29, Issue 4, pp. 238-244, (2017) (PubMed).

Yi, Liu, Xiang, Wang, Chen, Xie, Qi: "Akt and β-catenin contribute to TMZ resistance and EMT of MGMT negative malignant glioma cell line." in: Journal of the neurological sciences, Vol. 367, pp. 101-6, (2017) (PubMed).

Oktay, Ülgen, Can, Akyerli, Yüksel, Erdemgil, Durası, Henegariu, Nanni, Selevsek, Grossmann, Erson-Omay, Bai, Gupta, Lee, Turcan, Özpınar, Huse, Sav, Flanagan, Günel, Sezerman, Yakıcıer, Pamir et al.: "IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. ..." in: Scientific reports, Vol. 6, pp. 27569, (2016) (PubMed).

Stepanenko, Andreieva, Korets, Mykytenko, Baklaushev, Huleyuk, Kovalova, Kotsarenko, Chekhonin, Vassetzky, Avdieiev, Dmitrenko: "Temozolomide promotes genomic and phenotypic changes in glioblastoma cells." in: Cancer cell international, Vol. 16, pp. 36, (2016) (PubMed).

Ge, Guo, Zhang, Lin, Li, Liu, Kong, Fang, Zhao: "Impact of O6-methylguanine-DNA methyltransferase expression on the drug resistance of clear cell renal cell carcinoma." in: Japanese journal of clinical oncology, (2015) (PubMed).

Zheng, Xiong, Wu, Chen, Chen, Fleming, Gao, Bi, Ge: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).

Oláh, Kálmán, Tóth, Zvara, Sántha, Ivitz, Janka, Pákáski: "Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive." in: Journal of Alzheimer's disease : JAD, (2014) (PubMed).

Palmieri, Duchnowska, Woditschka, Hua, Qian, Biernat, Sosińska-Mielcarek, Gril, Stark, Hewitt, Liewehr, Steinberg, Jassem, Steeg: "Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 10, pp. 2727-39, (2014) (PubMed).

Synonyme und alternative Namen zu MGMT

O-6-methylguanine-DNA methyltransferase (MGMT), O-6-methylguanine-DNA methyltransferase (Mgmt), Agat, AGT, AI267024

Bezeichner auf Proteinebene für MGMT

  • 6-O-methylguanine-DNA methyltransferase
  • O-6-methylguanine-DNA-alkyltransferase
  • O6-methylguanine-DNA methyltransferase
  • methylated-DNA--protein-cysteine methyltransferase
  • methylguanine-DNA methyltransferase
  • O-6-alkylguanine-DNA alkyltransferase
  • 0-6-methylguanine-DNA methyltransferase
  • O(6)-alkylguanine-DNA alkyltransferase
  • O6-alkylguanine-DNA alkyltransferase
  • O6-methylguanine-DNA methyltranferase
  • O6-alkylguanine-DNA-alkyltransferase
  • O6-methylguanine-DNA-methyltransferase
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