MGMT Produkte
(O6-Methylguanine-DNA-Methyltransferase (MGMT))
Kategorien
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a
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Ausgewählte MGMT Kategorien
MGMT Antikörper
High quality antibodies with extensive validation data.
MGMT ELISA Kits
Reliable ELISA kits for a wide range of species.
MGMT Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MGMT Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA, FACS, ICC
Validierungen
- (7)
Kat. Nr.
ABIN5542437
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN730768
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7434551
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene MGMT ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6958286
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969037
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6958287
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MGMT Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7549405
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7563015
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124248
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MGMT Produkten
: "Effects of Some Growth Factors and Cytokines on the Expression of the Repair Enzyme MGMT and Protein MARP in Human Cells In Vitro : Effect of Some Growth Factors and Cytokines." in: Biochemical genetics, Vol. 56, Issue 5, pp. 459-477, (2018) (PubMed).: "PLK1 inhibition enhances temozolomide efficacy in IDH1 mutant gliomas." in: Oncotarget, Vol. 8, Issue 9, pp. 15827-15837, (2017) (PubMed).
: "MGMT gene variants, temozolomide myelotoxicity and glioma risk. A concise literature survey including an illustrative case." in: Journal of chemotherapy (Florence, Italy), Vol. 29, Issue 4, pp. 238-244, (2017) (PubMed).
: "Akt and β-catenin contribute to TMZ resistance and EMT of MGMT negative malignant glioma cell line." in: Journal of the neurological sciences, Vol. 367, pp. 101-6, (2017) (PubMed).
: "IDH-mutant glioma specific association of rs55705857 located at 8q24.21 involves MYC deregulation. ..." in: Scientific reports, Vol. 6, pp. 27569, (2016) (PubMed).
: "Temozolomide promotes genomic and phenotypic changes in glioblastoma cells." in: Cancer cell international, Vol. 16, pp. 36, (2016) (PubMed).
: "Impact of O6-methylguanine-DNA methyltransferase expression on the drug resistance of clear cell renal cell carcinoma." in: Japanese journal of clinical oncology, (2015) (PubMed).
: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).
: "Proteomic Analysis of Cerebrospinal Fluid in Alzheimer's Disease: Wanted Dead or Alive." in: Journal of Alzheimer's disease : JAD, (2014) (PubMed).
: "Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 20, Issue 10, pp. 2727-39, (2014) (PubMed).
Synonyme und alternative Namen zu MGMT
O-6-methylguanine-DNA methyltransferase (MGMT), O-6-methylguanine-DNA methyltransferase (Mgmt), Agat, AGT, AI267024Bezeichner auf Proteinebene für MGMT
- 6-O-methylguanine-DNA methyltransferase
- O-6-methylguanine-DNA-alkyltransferase
- O6-methylguanine-DNA methyltransferase
- methylated-DNA--protein-cysteine methyltransferase
- methylguanine-DNA methyltransferase
- O-6-alkylguanine-DNA alkyltransferase
- 0-6-methylguanine-DNA methyltransferase
- O(6)-alkylguanine-DNA alkyltransferase
- O6-alkylguanine-DNA alkyltransferase
- O6-methylguanine-DNA methyltranferase
- O6-alkylguanine-DNA-alkyltransferase
- O6-methylguanine-DNA-methyltransferase
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