anti-MAPK3 (MAPK3) Antikörper

Arabidopsis thaliana Mitogen-Activated Protein Kinase 3 (MAPK3) Interaktionspartner

1. MKK4 (zeige MAP2K4 Antikörper), MKK5 (zeige MAP2K5 Antikörper), MKK7 (zeige MAP2K7 Antikörper), and MKK9, are responsible for the activation of MPK3 and MPK6 (zeige MAPK6 Antikörper) by melatonin, indicating that melatonin-mediated innate immunity is triggered by MAPK (zeige MAPK1 Antikörper) signaling through MKK4 (zeige MAP2K4 Antikörper)/5/7/9-MPK3/6 cascades.

2. Phosphatase AP2C1, as well as AP2C1-targeted MPK3 and MPK6 (zeige MAPK6 Antikörper), are important regulators of plant-nematode interaction, where the co-ordinated action of these signalling components ensures the timely activation of plant defence.

3. Results demonstrated the contribution of MPK3 and MPK6 (zeige MAPK6 Antikörper) to riboflavin-induced resistance.

4. These results indicate that the MVB pathway is positively regulated by pathogen-responsive MPK3/6 through LIP5 phosphorylation and plays a critical role in plant immune system

5. MKK3-MPK6 is activated by blue light in a MYC2-dependent manner.

6. MPK3 and MPK6 (zeige MAPK6 Antikörper) target a subclass of 'VQ-motif'-containing proteins to regulate immune responses.

7. MicroRNA biogenesis factor DRB1 (zeige EPHX1 Antikörper) is a phosphorylation target of mitogen activated protein kinase (zeige MAPK1 Antikörper) MPK3 in both rice and Arabidopsis

8. MPK3 represses the constitutive and flg22-induced expression of defence genes in Arabidopsis thaliana.

9. These results suggest that the MKK9-MPK3/MPK6 (zeige MAPK6 Antikörper) cascade is part of the phosphate signaling pathway in plants.

10. AZI1 (zeige AZI1 Antikörper) overexpression in the mpk3 genetic background partially alleviates the salt-hypersensitive phenotype of this mutant, but functional MPK3 appears to be required for the full extent of AZI1 (zeige AZI1 Antikörper)-conferred robustness.

Cow (Bovine) Mitogen-Activated Protein Kinase 3 (MAPK3) Interaktionspartner

1. MAPK3/1 is involved in luteinizing hormone-mediated decrease of C-type natriuretic peptide (zeige NPPC Antikörper) and this process is related to the EGFR (zeige EGFR Antikörper) and MAPK3/1 signal pathways

2. Chronic hypoxia induces Egr-1 (zeige EGR1 Antikörper) via activation of ERK1/2 (zeige MAPK1/3 Antikörper) and contributes to pulmonary vascular remodeling.

3. ER Ca(2 (zeige CA2 Antikörper)+) release enhances eNOS (zeige NOS3 Antikörper) Ser (zeige SIGLEC1 Antikörper)-635 phosphorylation and function via ERK1/2 (zeige MAPK1/3 Antikörper) activation.

4. Thrombospondin 1 (zeige THBS1 Antikörper), fibronectin (zeige FN1 Antikörper), and vitronectin (zeige VTN Antikörper) are differentially dependent upon RAS, ERK1/2 (zeige MAPK1/3 Antikörper), and p38 (zeige MAPK14 Antikörper) for induction of vascular smooth muscle cell chemotaxis.

5. results suggest that Nav1.7-Ca2+ influx-protein kinase C-alpha pathway activated ERK1/ERK2 and p38, which increased phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation

6. These data suggest that Gab1 (zeige GAB1 Antikörper)-ERK1/2 (zeige MAPK1/3 Antikörper) binding and their nuclear translocation play a crucial role in Egr-1 (zeige EGR1 Antikörper) nuclear accumulation.

7. data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (zeige AKT1 Antikörper), mTOR (zeige FRAP1 Antikörper), p70S6K (zeige RPS6KB1 Antikörper), and ERK1/2 (zeige MAPK1/3 Antikörper).

8. This study demonstrates for the first time that cyclic mechanical stretch induces the proliferation of bovine satellite cells and suppresses their myogenic differentiation through the activation of ERK (zeige MAPK1 Antikörper).

9. findings indicate that exposure to DHEA, at concentrations found in human blood, causes vascular endothelial proliferation by a plasma membrane-initiated activity that is Gi/o and ERK1/2 (zeige MAPK1/3 Antikörper) dependent.

10. Results suggest that estrogen receptors and the ERK1/2 (zeige MAPK1/3 Antikörper) signaling pathway are involved in the anti-apoptotic action of LY117018 in vascular endothelial cells.

Candida albicans Mitogen-Activated Protein Kinase 3 (MAPK3) Interaktionspartner

1. Cek2 (zeige FGFR3 Antikörper) has a cryptic role in cell-wall biogenesis and its role is not entirely redundant to Cek1.

2. knockdown of SUV420H1 (zeige SUV420H1 Antikörper) reduced phosphorylated ERK1 and total ERK1 proteins, and interestingly suppressed ERK1 at the transcriptional level

3. Secreted aspartic protease-mediated proteolytic cleavage of Msb2 is required for activation of the Cek1 mitogen activated protein kinase (zeige MAPK1 Antikörper) pathway in response to environmental cues.

4. The authors propose that a Msb2, Cek1 and Ace2 signalling pathway addresses PMT genes as downstream targets and that different modes of regulation have evolved for PMT1 and PMT2/PMT4 genes.

5. Msb2 is involved in the transmission of the signal toward Cek1 mediated by the Cdc42 (zeige CDC42 Antikörper) GTPase (zeige RACGAP1 Antikörper).

Zebrafish Mitogen-Activated Protein Kinase 3 (MAPK3) Interaktionspartner

1. ERK1/2 (zeige MAPK1/3 Antikörper)-Akt1 (zeige AKT1 Antikörper) crosstalk regulates arteriogenesis in mice and zebrafish.

2. eena (zeige SH3GL1 Antikörper) plays an important role in the development of the myeloid cell through activation of the ERK1/ERK2 (zeige MAPK1 Antikörper) pathway

3. ERK1 and ERK2 (zeige MAPK1 Antikörper) target common and distinct gene sets, confirming diverse roles for these kinases during embryogenesis; for ERK1 different specific genes involved in dorsal-ventral patterning and subsequent embryonic cell migration were identified.

4. These results demonstrate that induction of Hsp70 (zeige HSPA1A Antikörper) in response to heat stress is dependent on ERK (zeige MAPK1 Antikörper) activation in Pac2 (zeige PSMG2 Antikörper) cells.

5. Data define distinct roles for ERK1 and ERK2 (zeige MAPK1 Antikörper) in developmental cell migration processes during zebrafish embryogenesis.

Human Mitogen-Activated Protein Kinase 3 (MAPK3) Interaktionspartner

1. Finally, the authors show that EGFR (zeige EGFR Antikörper)-ERK1/2 (zeige MAPK1/3 Antikörper) and beta1-integrin signaling are the main pathways used for bacteria-mediated EGR1 (zeige EGR1 Antikörper) upregulation.

2. ERK1 phosphorylation is mediated by Src (zeige SRC Antikörper) and Csk (zeige CSK Antikörper).

3. Integrin beta1 appears to serve as a partner of Stathmin (zeige STMN1 Antikörper) induction of ERK (zeige EPHB2 Antikörper) and Akt (zeige AKT1 Antikörper) signaling by inhibiting apoptosis in the cholangiocarcinoma cell.

4. Aberrant expression of sema3c (zeige SEMA3C Antikörper) is correlated with poor prognosis of pancreatic ductal adenocarcinoma patients and promotes tumor growth and metastasis by activating ERK1/2 (zeige MAPK1/3 Antikörper) signaling pathway.

5. Increased staining for phosphorylated ERK1/2 does not correlate to BRAF or KRAS mutations in colorectal neoplasms.

6. Mutations of MAP2K1 (zeige MAP2K1 Antikörper) are frequent in pediatric-type follicular lymphoma and result in ERK1/ERK2 (zeige MAPK1 Antikörper) pathway activation.

7. Data show that succinate upregulates vascular endothelial growth factor (VEGF) expression by activation of signal transducer and activator of transcription 3 (STAT3 (zeige STAT3 Antikörper)) and extracellular regulated kinase (ERK)1/2 via its receptor G-protein coupled receptor 91 (GPR91 (zeige SUCNR1 Antikörper)).

8. data suggest that the ERK1/2 (zeige MAPK1/3 Antikörper) pathway plays an important role in the regulation of HNF4alpha (zeige HNF4A Antikörper)-dependent hepatic gene expression.

9. phosphorylation by ERK (zeige EPHB2 Antikörper) also regulates the association of HIF-1alpha (zeige HIF1A Antikörper) with a so-far-unknown interaction partner identified as mortalin (zeige HSPA9 Antikörper) (also known as GRP75 (zeige HSPA9 Antikörper) and HSPA9 (zeige HSPA9 Antikörper)), which mediates non-genomic involvement of HIF-1alpha (zeige HIF1A Antikörper) in apoptosis.

10. ROS (zeige ROS1 Antikörper) activation of the MAPK (ERK (zeige MAPK1 Antikörper)-1/2)/Egr-1 (zeige EGR1 Antikörper) pathway is a main player in the regulatory mechanism for cigarette smoke extract-induced PlGF (zeige PGF Antikörper) production. Antioxidants could partly abolish these effects.

Mouse (Murine) Mitogen-Activated Protein Kinase 3 (MAPK3) Interaktionspartner

1. Studies indicate that progesterone receptor (zeige PGR Antikörper) transgenic (Pgrcre/+) mitogen inducible gene 6 (Mig (zeige CXCL9 Antikörper)-6over) phosphatase and tensin homolog (zeige PTEN Antikörper) protein (Ptenf/f) knockout mice exhibited an increase of phospho-ERK1/2 (zeige MAPK1/3 Antikörper) and its target genes.

2. Gpr182 reduction led to increased activation of ERK1/2 in basal and challenge models, demonstrating a potential role for this orphan GPCR in regulating the proliferative capacity of the intestine.

3. ERK1 underexpression is associated with obesity.

4. retinoschisin (zeige RS1 Antikörper) is a novel regulator of MAP kinase (zeige MAPK1 Antikörper) signalling and exerts an anti-apoptotic effect on retinal cells.

5. Postnatal chondrocyte-specific deletion of Hdac3 (zeige HDAC3 Antikörper) with an inducible Col2a1 (zeige COL2A1 Antikörper)-Cre caused premature production of pErk1/2 and Mmp13 (zeige MMP13 Antikörper) in the growth plate.

6. The progress of neurogenesis depended on sustained ERK (zeige EPHB2 Antikörper) phosphorylation and resulted in ERK1/2 (zeige MAPK1/3 Antikörper) translocation to the nucleus.

7. Mirtazapine suppressed 5-HT (zeige DDC Antikörper)-mediated TGF-beta1 (zeige TGFB1 Antikörper)/Smad3 (zeige SMAD3 Antikörper) and ERK1/2 (zeige MAPK1/3 Antikörper) signaling pathways as well as oxidative stress that contribute to the progression of liver fibrosis.

8. The kinase TPL2 (zeige MAP3K8 Antikörper) activates ERK (zeige EPHB2 Antikörper) and p38 (zeige CRK Antikörper) signaling to promote neutrophilic inflammation

9. HAS2 (zeige HAS2 Antikörper)-produced hyaluronan is required for CD44V6 and TGFbetaRI co-localization and subsequent CD44V6/ERK1/EGR1 (zeige EGR1 Antikörper) signaling. These results demonstrate a novel positive-feedback loop that links the myofibroblast phenotype to TGFbeta1 (zeige TGFB1 Antikörper)-stimulated CD44V6/ERK (zeige EPHB2 Antikörper)/EGR1 (zeige EGR1 Antikörper) signaling.

10. We also demonstrated that ERK1 deletion potentiates DC vaccination and provides a survival advantage in high-grade gliomas.

Pig (Porcine) Mitogen-Activated Protein Kinase 3 (MAPK3) Interaktionspartner

1. Pseudorabies virus glycoprotein gE-mediated ERK 1/2 phosphorylation also occurs in epithelial cells and in these cells, gE-mediated ERK 1/2 signaling is associated with degradation of the pro-apoptotic protein Bim (zeige BCL2L11 Antikörper).

2. Treatment with ERK (zeige MAPK1 Antikörper) inhibitors or ERK1/2 (zeige MAPK1/3 Antikörper) knockdown significantly suppressed porcine epidemic diarrhea virus progeny production.

3. This study reveals a new function of the gE glycoprotein of pseudorabies virus and suggests that pseudorabies virus, through activation of ERK1/2 (zeige MAPK1/3 Antikörper) signaling, has a substantial impact on T cell behavior.

4. CSF2 (zeige CSF2 Antikörper) stimulates proliferation of trophectoderm cells by activation of the PI3K-and ERK1/2 (zeige MAPK1/3 Antikörper) MAPK (zeige MAPK1 Antikörper)-dependent MTOR (zeige FRAP1 Antikörper) signal transduction cascades.

5. PGRN (zeige GRN Antikörper) inhibits adipogenesis in porcine preadipocytes partially through ERK (zeige MAPK1 Antikörper) activation mediated PPARgamma (zeige PPARG Antikörper) phosphorylation.

6. Porcine circovirus type 2 (PCV2) might induce autophagy via the AMPK (zeige PRKAA1 Antikörper)/ERK (zeige MAPK1 Antikörper)/TSC2 (zeige TSC2 Antikörper)/mTOR (zeige FRAP1 Antikörper) signaling pathway in the host cells, representing a pivotal mechanism for PCV2 pathogenesis

7. Data show that proinflammatory cytokines induction was ERK1/2 (zeige MAPK1/3 Antikörper) and JNK1 (zeige MAPK8 Antikörper)/2 dependent.

8. Saccharomyces cerevisiae inhibits the Enterotoxigenic Escherichia coli-induced expression of pro-inflammatory transcripts and this inhibition was associated to a decrease of ERK1/2 (zeige MAPK1/3 Antikörper) and p38 MAPK (zeige MAPK14 Antikörper) phosphorylation

9. ERK1 phosphorylation in response to Insulin-like Growth Factor-1 (zeige IGF1 Antikörper) does not require activation of the Insulin-like Growth Factor-1 receptor tyrosine kinase (zeige IGF1R Antikörper)

10. Retinal ischemia-reperfusion alters expression of mitogen-activated protein kinases, particularly ERK1/2 (zeige MAPK1/3 Antikörper), in the neuroretina and retinal arteries.