Protein Überblick

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.

Alternative names and synonyms associated with MAP2K2

• mitogen-activated protein kinase kinase 2 (MAP2K2) Antikörper
• mitogen-activated protein kinase kinase 2 (Map2k2) Antikörper
• mitogen activated protein kinase kinase 2 (Map2k2) Antikörper
• MAP kinase kinase 2 (MKK2) Antikörper
• mitogen-activated protein kinase kinase 2b (map2k2b) Antikörper

• AA589381 Antikörper
• ATMKK2 Antikörper
• CFC4 Antikörper
• F27B13.50 Antikörper
• F27B13_50 Antikörper
• Alle Synonyme
• MAP KINASE KINASE 1 Antikörper
• MAP kinase kinase 2 Antikörper
• MAPKK2 Antikörper
• MEK2 Antikörper
• MK1 Antikörper
• MK2 Antikörper
• MKK2 Antikörper
• Prkmk2 Antikörper
• zgc:172250 Antikörper

Bezeichner auf Proteinebene für MAP2K2

ERK activator kinase 2 , MAP kinase kinase 2 , MAPK/ERK kinase 2 , dual specificity mitogen-activated protein kinase kinase 2 , mitogen-activated protein kinase kinase 2, p45 , MAP kinase/Erk kinase , MAPKK 2 , MEK 2 , mitogen activated protein kinase kinase 2 , protein kinase, mitogen activated, kinase 2, p45 , MEK2 , mitogen-activated protein kinase kinase type 2 , dual specificity mitogen activated protein kinase kinase 2