MASP1 Produkte
(Mannan-Binding Lectin Serine Peptidase 1 (MASP1))
Kategorien
This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010].
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Ausgewählte MASP1 Kategorien
MASP1 Antikörper
High quality antibodies with extensive validation data.
MASP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
MASP1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MASP1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, ICC, IHC (p), IHC (fro)
Validierungen
- (6)
Kat. Nr.
ABIN7434299
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7434302
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF (p), IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN733508
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene MASP1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN6957634
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6957635
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968437
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MASP1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1310414
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505079
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
Kat. Nr.
ABIN7583275
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MASP1 Produkten
: "Plasma proteome profiling of high-altitude polycythemia using TMT-based quantitative proteomics approach." in: Journal of proteomics, Vol. 194, pp. 60-69, (2020) (PubMed).: "AmpliSeq Screening of Genes Encoding the C-Type Lectin Receptors and Their Signaling Components Reveals a Common Variant in MASP1 Associated with Pulmonary Tuberculosis in an Indian Population." in: Frontiers in immunology, Vol. 9, pp. 242, (2019) (PubMed).
: "Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis." in: Journal of neuroinflammation, Vol. 14, Issue 1, pp. 2, (2017) (PubMed).
: "The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary Angioedema." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 8, pp. 3596-604, (2015) (PubMed).
: "Bisretinoid-mediated complement activation on retinal pigment epithelial cells is dependent on complement factor H haplotype." in: The Journal of biological chemistry, Vol. 289, Issue 13, pp. 9113-20, (2014) (PubMed).
: "The biological functions of MBL-associated serine proteases (MASPs)." in: Immunobiology, Vol. 205, Issue 4-5, pp. 467-75, (2002) (PubMed).
: "Functional characterization of human mannose-binding lectin-associated serine protease (MASP)-1/3 and MASP-2 promoters, and comparison with the C1s promoter." in: International immunology, Vol. 14, Issue 10, pp. 1193-201, (2002) (PubMed).
: "Expression of H-ficolin/Hakata antigen, mannose-binding lectin-associated serine protease (MASP)-1 and MASP-3 by human glioma cell line T98G." in: International immunology, Vol. 15, Issue 1, pp. 109-17, (2002) (PubMed).
: "The mannan-binding lectin-associated serine proteases (MASPs) and MAp19: four components of the lectin pathway activation complex encoded by two genes." in: Immunobiology, Vol. 205, Issue 4-5, pp. 455-66, (2002) (PubMed).
: "Activation of the lectin complement pathway by H-ficolin (Hakata antigen)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 7, pp. 3502-6, (2002) (PubMed).
Synonyme und alternative Namen zu MASP1
mannan-binding lectin serine peptidase 1 (Masp1), mannan binding lectin serine peptidase 1 (MASP1), 3MC1, AW048060, CCPII, Crarf, CRARF, CRARF1, MAP1, MAp44, MASP, Masp1/3, MASP3, PRSS5, RaRFBezeichner auf Proteinebene für MASP1
- MASP-1
- complement factor MASP-3
- complement-activating component of Ra-reactive factor
- mannan-binding lectin serine protease 1
- mannose-binding lectin-associated serine protease 1
- mannose-binding protein-associated serine protease
- ra-reactive factor serine protease p100
- raRF
- serine protease 5
- Ra-reactive factor serine protease p100
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