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MARCH1 Proteine

(Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase (MARCH1))
MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]\; Thibodeau et al., 2008 [PubMed 18389477]\; De Gassart et al., 2008 [PubMed 18305173]).[supplied by OMIM, Mar 2010].

1 Treffer

MARCH1 Spezies: Human Wirt: Wheat germ Recombinant AP, AA, ELISA, WB
Produktnummer ABIN1310352
 
  • Typ Protein
    • Protein
  • Anwendung
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • ELISA
    • Western Blotting (WB)
  • Reaktivität
    • Human
  • Abbildungen verfügbar
  • Wirt
    • Wheat germ
  • Bindungsspezifität
    • AA 1-272
  • Konjugat
    • GST tag
  • Protein-Typ
    • Recombinant
  • Hersteller
    • antibodies-online

Aliase für MARCH1 Proteine

membrane associated ring-CH-type finger 1 (MARCH1) Proteine
membrane-associated ring finger (C3HC4) 1 (March1) Proteine
membrane associated ring-CH-type finger 1 (March1) Proteine
2900024D24Rik Proteine
BB085186 Proteine
DKFZp459K1250 Proteine
MARCH-I Proteine
MARCH1 Proteine
RGD1305148 Proteine
RNF171 Proteine
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