MAP4K4 Proteine
(Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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MAP4K4
Spezies: Human
Wirt: Insektenzellen
Recombinant
70 % - 90 %
Func
Active
Aliase für MAP4K4 Proteine
mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) Proteinemitogen-activated protein kinase kinase kinase kinase 4 (Map4k4) Proteine
9430080K19Rik Proteine
AU043147 Proteine
AU045934 Proteine
AW046177 Proteine
FLH21957 Proteine
HGK Proteine
MEKKK4 Proteine
NIK Proteine
Nik Proteine
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- MAP4K3 Proteine
- MAP4K2 Proteine
- MAP4K1 Proteine
- MAP4 Proteine
- MAP3K9 Proteine
- MAP3K8 Proteine
- MAP3K7CL Proteine
- MAP3K7 Proteine
- MAP3K6 Proteine
- MAP3K4 Proteine
- MAP3K2 Proteine
- MAP3K19 Proteine
- MAP3K15 Proteine
- MAP3K14 Proteine
- MAP3K12 Proteine
- MAP3K11 Proteine
- MAP3K10 Proteine
- MAP3K1 Proteine
- MAP2K7 Proteine
- MAP2K6 Proteine
- MAP4K5 Proteine
- MAP4K6 Proteine
- MAP6 Proteine
- MAP6D1 Proteine
- MAP9 Proteine
- MAPK10 Proteine
- MAPK11 Proteine
- MAPK12 Proteine
- MAPK13 Proteine
- MAPK14 Proteine
- MAPK15 Proteine
- MAPK4 Proteine
- MAPK6 Proteine
- MAPK7 Proteine
- MAPK8IP1 Proteine
- MAPKAP Kinase 2 Proteine
- MAPKAP Kinase 3 Proteine
- MAPKAP Kinase 5 Proteine
- MAPKAP1 Proteine
- MAPKBP1 Proteine
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