MAP3K7 Proteine
(Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2\; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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MAP3K7
Spezies: Human
Wirt: Wheat germ
Recombinant
ELISA, WB, AP, AA, KAA
1 image
3 Referenzen
MAP3K7
Spezies: Human
Wirt: Wheat germ
Recombinant
ELISA, WB, AP, AA
1 image
MAP3K7
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
ELISA, WB, SDS
custom-made
MAP3K7
Spezies: Maus
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
custom-made
MAP3K7
Spezies: Human
Wirt: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
ELISA, WB, SDS
MAP3K7
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
Aktuelle Publikationen für unsere MAP3K7 Proteine
: "Fibroblast growth factor receptor 3 interacts with and activates TGF?-activated kinase 1 tyrosine phosphorylation and NF?B signaling in multiple myeloma and bladder cancer." in: PLoS ONE, Vol. 9, Issue 1, pp. e86470, (2014) (PubMed).: "The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner." in: Nature cell biology, Vol. 10, Issue 10, pp. 1199-207, (2008) (PubMed).
: "CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages." in: Blood, Vol. 112, Issue 13, pp. 4961-70, (2008) (PubMed).
Aliase für MAP3K7 Proteine
mitogen-activated protein kinase kinase kinase 7 (map3k7) Proteinemitogen activated protein kinase kinase kinase 7 (Map3k7) Proteine
mitogen-activated protein kinase kinase kinase 7 (MAP3K7) Proteine
mitogen-activated protein kinase kinase kinase 7 (Map3k7) Proteine
B430101B05 Proteine
C87327 Proteine
MEKK7 Proteine
si:ch211-225h9.1 Proteine
Tak1 Proteine
TAK1 Proteine
TGF1a Proteine
zgc:110612 Proteine
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- MAP3K15 Proteine
- MAP3K14 Proteine
- MAP3K12 Proteine
- MAP3K11 Proteine
- MAP3K10 Proteine
- MAP3K1 Proteine
- MAP2K7 Proteine
- MAP2K6 Proteine
- MAP2K5 Proteine
- MAP2K3 Proteine
- MAP2 Proteine
- MAP1S Proteine
- MAP1LC3B2 Proteine
- MAP1LC3A Proteine
- MAP1D Proteine
- MAP1B Proteine
- MAP3K7CL Proteine
- MAP3K8 Proteine
- MAP3K9 Proteine
- MAP4 Proteine
- MAP4K1 Proteine
- MAP4K2 Proteine
- MAP4K3 Proteine
- MAP4K4 Proteine
- MAP4K5 Proteine
- MAP4K6 Proteine
- MAP6 Proteine
- MAP6D1 Proteine
- MAP9 Proteine
- MAPK10 Proteine
- MAPK11 Proteine
- MAPK12 Proteine
- MAPK13 Proteine
- MAPK14 Proteine
- MAPK15 Proteine
- MAPK4 Proteine
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