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MAK Produkte

(Male Germ Cell-Associated Kinase (MAK))

Kategorien

The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011].

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Ausgewählte MAK Kategorien

MAK Antikörper

High quality antibodies with extensive validation data.

MAK ELISA Kits

Reliable ELISA kits for a wide range of species.

MAK Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MAK Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (6)
Kat. Nr. ABIN517720
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
  • (3)
Kat. Nr. ABIN391782
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7268382
Menge 100 μL
Datenblatt Datenblatt

Empfohlene MAK ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1381289
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MAK Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1310104
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1310103
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
Kat. Nr. ABIN5508993
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MAK Produkten

Li, Rao, Zheng-Le, Hurd, Lillo, Khanna: "Loss of retinitis pigmentosa 2 (RP2) protein affects cone photoreceptor sensory cilium elongation in mice." in: Cytoskeleton (Hoboken, N.J.), (2015) (PubMed).

Tucker, Scheetz, Mullins, DeLuca, Hoffmann, Johnston, Jacobson, Sheffield, Stone: "Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pigmentosa." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 34, pp. E569-76, (2011) (PubMed).

Ma, Xia, Desai, Boucher, Guan, Shih, Shi, deVere White, Chen, Tepper, Kung: "Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells." in: Cancer research, Vol. 66, Issue 17, pp. 8439-47, (2006) (PubMed).

Fu, Larson, Chitta, Parker, Turk, Lawrence, Kaldis, Galaktionov, Cohn, Shabanowitz, Hunt, Sturgill: "Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase." in: Molecular and cellular biology, Vol. 26, Issue 22, pp. 8639-54, (2006) (PubMed).

Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).

Xia, Robinson, Ma, Chen, Wu, Qiu, Kung: "Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells." in: The Journal of biological chemistry, Vol. 277, Issue 38, pp. 35422-33, (2002) (PubMed).

Woodle, Newman, Cohen: "Sterically stabilized liposomes: physical and biological properties." in: Journal of drug targeting, Vol. 2, Issue 5, pp. 397-403, (1995) (PubMed).

Synonyme und alternative Namen zu MAK

male germ cell associated kinase (MAK), male germ cell-associated kinase (Mak), male germ cell-associated kinase (mak), male germ cell associated kinase L homeolog (mak.L), male germ cell associated kinase (mak), A930010O05Rik, dJ417M14.2, fj04c02, Ick, MGC82717, MGC146434, RP62, rp62, wu:fj04c02, xmak, zgc:56603

Bezeichner auf Proteinebene für MAK

  • male germ cell-associated kinase retinal-enriched isoform
  • serine/threonine protein kinase MAK
  • serine/threonine-protein kinase MAK
  • protein kinase RCK
  • intestinal cell kinase
  • male germ cell-associated kinase
  • serine/threonine-protein kinase MAK-like
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