PPP1R12A ELISA Kit

6 products by 4 suppliers: Assay Biotechnology | Aviva Systems Biology | Abbexa | Abnova
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PPP1R12A ELISA Kit
$480.00
96 tests
Human
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PPP1R12A ELISA Kit
$480.00
96 tests
Mouse (Murine)
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PPP1R12A ELISA Kit
$480.00
96 tests
Rat (Rattus)
Recommendations are based on data provided indicating:
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  • ELISA Kit Specificity
    The recommended ELISA Kit will likely detect the antigen in question with higher specificity in approved samples than the available alternatives.
  • Experiement Reproducibility
    The results will be likely more reproducible, with high inter- or intra-assay CV and Recovery (for values within the std curve) than the available alternatives.
  • ELISA Kit Robustness
    The recommended assay will likely function better with approved sample types, and will not suffer from undue matrix interference than the available alternatives.
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PPP1R12A Antigen Profile

Beschreibung des Gens

Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells. The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP.RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC. Rho-associated kinase (Rho-kinase), which is activated by GTP. RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase. Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC. Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase. Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with PPP1R12A

  • protein phosphatase 1, regulatory (inhibitor) subunit 12A (Ppp1r12a) ELISA Kit
  • protein phosphatase 1 regulatory subunit 12A (PPP1R12A) ELISA Kit
  • protein phosphatase 1, regulatory subunit 12A (Ppp1r12a) ELISA Kit
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Bezeichner auf Proteinebene für PPP1R12A

myosin phosphatase target subunit 1 , myosin phosphatase, target subunit 1 , myosin phosphatase-targeting subunit 1 , protein phosphatase 1 regulatory subunit 12A , myosin binding subunit , protein phosphatase 1, regulatory (inhibitor) subunit 12A , protein phosphatase myosin-binding subunit , PP-1M , protein phosphatase subunit 1M , serine/threonine protein phosphatase PP1 smooth muscle regulatory subunit M110 , smooth muscle myosin phosphatase myosin-binding subunit , 130 kDa myosin-binding subunit of smooth muscle myosin phophatase , 130 kDa myosin-binding subunit of smooth muscle myosin phosphatase , 133kDa myosin-binding subunit of smooth muscle myosin phosphatase (M133) , PP1M subunit M110

GENE ID SPEZIES
17931 Mus musculus
4659 Homo sapiens
116670 Rattus norvegicus
396020 Gallus gallus
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