Lysophosphatidic Acid Receptor 3 (EDG-7) Lysate
Kurzübersicht für Lysophosphatidic Acid Receptor 3 (EDG-7) Lysate (ABIN2764010)
Target
Applikation
Lysate Fraction
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Produktmerkmale
- EDG7 (LPA3) Transfected Cell Positive Control Lysate,Endothelial Cell Differentiation Gene-7 (EDG7) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG7 is lysophospholipid. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG7 is expressed in prostate as well as other tissues.
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Applikationshinweise
- For use as a positive control with EDG7 monoclonal antibody (ABIN306802) for Western blot analysis.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Provided in 10 % glycerol, 0.063 M Tris-HCl ( pH 6.8), 2 % SDS and 0.002 % bromophenol blue, 5 % 2-mercaptoethanol
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- LPAR3 (Lysophosphatidic Acid Receptor 3 (LPAR3))
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Andere Bezeichnung
- Lysophosphatidic Acid Receptor 3 (EDG-7)
Target
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