ABCG8 Proteine

Protein Überblick

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.

Alternative names and synonyms associated with ABCG8

• ATP binding cassette subfamily G member 8 (ABCG8) Antikörper
• ATP-binding cassette sub-family G member 8 (PTRG_02054) Antikörper
• ABC transporter G family protein (abcG8) Antikörper
• ATP-binding cassette, sub-family G (WHITE), member 8 (abcg8) Antikörper
• ATP binding cassette subfamily G member 8 (Abcg8) Antikörper

• 1300003C16Rik Antikörper
• AI114946 Antikörper
• DDBDRAFT_0167690 Antikörper
• DDBDRAFT_0191232 Antikörper
• DDB_0167690 Antikörper
• Alle Synonyme
• DDB_0191232 Antikörper
• GBD4 Antikörper
• sterolin-2 Antikörper
• STSL Antikörper
• zgc:172358 Antikörper

Bezeichner auf Proteinebene für ABCG8

ATP-binding cassette, sub-family G (WHITE), member 8 (sterolin 2) , sterolin 2 , ATP-binding cassette sub-family G member 8 , sterolin-2 , ATP-binding cassette, sub-family G (WHITE), member 8 , ATP-binding cassette sub-family G member 8-like , ATP-binding cassette, subfamily G, member 8