Lipin 1 Produkte
(Lipin 1 (LPIN1))
Kategorien
This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined. [provided by RefSeq, May 2012].
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Ausgewählte Lipin 1 Kategorien
Lipin 1 Antikörper
High quality antibodies with extensive validation data.
Lipin 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Lipin 1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Lipin 1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7436306
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, IHC (p)
Validierungen
- (3)
- (2)
Kat. Nr.
ABIN540690
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7163118
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Lipin 1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957497
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957498
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957499
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Lipin 1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1309703
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1309702
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3093621
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Lipin 1 Produkten
: "C1q/tumor necrosis factor-related protein 11 (CTRP11), a novel adipose stroma-derived regulator of adipogenesis." in: The Journal of biological chemistry, Vol. 288, Issue 15, pp. 10214-29, (2013) (PubMed).: "Expression of cyclins-B and cyclins-e in individual molt-4 cells and in stimulated human-lymphocytes during their progression through the cell-cycle." in: International journal of oncology, Vol. 3, Issue 6, pp. 1037-42, (2011) (PubMed).
: "Estrogen-related receptor γ (ERRγ) is a novel transcriptional regulator of phosphatidic acid phosphatase, LIPIN1, and inhibits hepatic insulin signaling." in: The Journal of biological chemistry, Vol. 286, Issue 44, pp. 38035-42, (2011) (PubMed).
: "Subcellular localization and role of lipin-1 in human macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 10, pp. 6004-13, (2011) (PubMed).
: "Characterization of the human LPIN1-encoded phosphatidate phosphatase isoforms." in: The Journal of biological chemistry, Vol. 285, Issue 19, pp. 14628-38, (2010) (PubMed).
: "Cross-species analyses implicate Lipin 1 involvement in human glucose metabolism." in: Human molecular genetics, Vol. 15, Issue 3, pp. 377-86, (2006) (PubMed).
: "Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway." in: Cell metabolism, Vol. 4, Issue 3, pp. 199-210, (2006) (PubMed).
: "The Saccharomyces cerevisiae Lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9210-8, (2006) (PubMed).
: "Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis." in: The Journal of biological chemistry, Vol. 280, Issue 38, pp. 32883-9, (2005) (PubMed).
: "Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 2, pp. 1047-52, (2002) (PubMed).
Synonyme und alternative Namen zu Lipin 1
lipin 1 (LPIN1), lipin 1 (lpin1), phosphatidate phosphatase LPIN1 (LOC100539289), lipin 1 (Lpin1), 4631420P06, fld, Kiaa0188, Lipin1, lipin1, LPIN1, mKIAA0188, pap1, PAP1, zgc:194552, zgc:194558Bezeichner auf Proteinebene für Lipin 1
- lipin 1
- phosphatidate phosphatase LPIN1-like
- lipin-1
- phosphatidate phosphatase LPIN1
- fatty liver dystrophy protein
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