LAG3 Proteine
(Lymphocyte-Activation Gene 3 (LAG3))
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008].
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LAG3
Spezies: Human
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
LAG3
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
LAG3
Spezies: Maus
Wirt: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
LAG3
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
LAG3
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
LAG3
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
LAG3
Spezies: Ratte
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
1 image
LAG3
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
1 image
LAG3
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
LAG3
Spezies: Cynomolgus
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
MALS verified
LAG3
Spezies: Hund
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
LAG3
Spezies: Human
Wirt: Human Cells
Recombinant
Greater than 95 % as determined by reducing SDS-PAGE.
WB, SDS, ELISA, MS
LAG3
Spezies: Cynomolgus
Wirt: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
LAG3
Spezies: Cynomolgus
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
MALS verified
LAG3
Spezies: Maus
Wirt: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
Aktuelle Publikationen für unsere LAG3 Proteine
: "Peptide-based PET tracer targeting LAG-3 for evaluating the efficacy of immunotherapy in melanoma." in: Journal for immunotherapy of cancer, Vol. 12, Issue 7, (2024) (PubMed).: "Characterization of a novel anti-human lymphocyte activation gene 3 (LAG-3) antibody for cancer immunotherapy." in: mAbs, Vol. 11, Issue 6, pp. 1139-1148, (2019) (PubMed).
: "A signal-decreased electrochemical immunosensor for the sensitive detection of LAG-3 protein based on a hollow nanobox-MOFs/AuPt alloy." in: Biosensors & bioelectronics, Vol. 113, pp. 148-156, (2018) (PubMed).
: "A soluble form of lymphocyte activation gene-3 (IMP321) induces activation of a large range of human effector cytotoxic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 4202-11, (2007) (PubMed).
: "A soluble lymphocyte activation gene-3 (sLAG-3) protein as a prognostic factor in human breast cancer expressing estrogen or progesterone receptors." in: Cancer letters, Vol. 235, Issue 1, pp. 147-53, (2006) (PubMed).
: "LAG-3 (CD223) reduces macrophage and dendritic cell differentiation from monocyte precursors." in: Immunology, Vol. 114, Issue 3, pp. 369-74, (2005) (PubMed).
: "LAG-3 enables DNA vaccination to persistently prevent mammary carcinogenesis in HER-2/neu transgenic BALB/c mice." in: Cancer research, Vol. 63, Issue 10, pp. 2518-25, (2003) (PubMed).
: "Maturation and activation of dendritic cells induced by lymphocyte activation gene-3 (CD223)." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 8, pp. 3874-80, (2002) (PubMed).
: "T cell major histocompatibility complex class II molecules down-regulate CD4+ T cell clone responses following LAG-3 binding." in: European journal of immunology, Vol. 26, Issue 5, pp. 1180-6, (1996) (PubMed).
: "CD4/major histocompatibility complex class II interaction analyzed with CD4- and lymphocyte activation gene-3 (LAG-3)-Ig fusion proteins." in: European journal of immunology, Vol. 25, Issue 9, pp. 2718-21, (1995) (PubMed).
Aliase für LAG3 Proteine
lymphocyte activating 3 (LAG3) Proteinelymphocyte-activation gene 3 (Lag3) Proteine
lymphocyte activating 3 (Lag3) Proteine
CD223 Proteine
LAG-3 Proteine
Ly66 Proteine
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