anti-FCN3 (FCN3) Antikörper

Auf finden Sie aktuell 45 Ficolin (Collagen/fibrinogen Domain Containing) 3 (Hakata Antigen) (FCN3) Antikörper von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen FCN3 Kits (16) und FCN3 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 72 FCN3 Produkte verfügbar.
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FCN3 8547 O75636

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Human Ficolin (Collagen/fibrinogen Domain Containing) 3 (Hakata Antigen) (FCN3) Interaktionspartner

  1. results suggest that anti-ficolin-3 antibodies could be useful for the diagnosis of active nephritis in SLE patients

  2. this study shows that H-ficolin may aid clearance of influenza A virus by promoting monocyte uptake of the virus, while reducing viral replication and virus-induced TNF-a (zeige TNF Antikörper) responses in these cells

  3. These results suggest that polymorphisms in the FCN3 gene cooperate to increase ficolin-3 concentration and that it might contribute to leprosy susceptibility by favoring Mycobacterium leprae infection.

  4. subjects that were heterozygote carriers of both FCN2 (zeige FCN2 Antikörper) + 6424 and FCN3 + 1637delC were sufficient mannan-binding lectin (zeige MBL2 Antikörper) producers

  5. in patients with systemic lupus erythematosus, there was no significant association between ficolin-1 (zeige FCN1 Antikörper) and ficolin-3 with lupus nephritis

  6. Monitoring serum H-ficolin levels was shown to be of no benefit in terms of predicting severe infection.

  7. Serum levels of ficolin-2 (zeige FCN2 Antikörper) and ficolin-3 were significantly lower in the cardiac syndrome X patients compared to controls.

  8. LPS induces a tissue-specific recruitment of ficolin-3 and ficolin-1 in the lung and systemic compartment, respectively, suggesting an important role of distinct lectin complement pathway initiators in the local pulmonary and systemic host defence.

  9. Lower serum ficolin-3 levels were correlated with injury severity following traumatic brain injury.

  10. this study provide novel insight in the binding and complement activating capacity of the lectin pathway initiation molecules ficolin-2 (zeige FCN2 Antikörper) and ficolin-3 towards relevant Gram-negative pathogens of pathophysiological relevance.

FCN3 Antigen-Profil

Beschreibung des Gens

Ficolins are a group of proteins which consist of a collagen-like domain and a fibrinogen-like domain. In human serum, there are two types of ficolins, both of which have lectin activity. The protein encoded by this gene is a thermolabile beta-2-macroglycoprotein found in all human serum and is a member of the ficolin/opsonin p35 lectin family. The protein, which was initially identified based on its reactivity with sera from patients with systemic lupus erythematosus, has been shown to have a calcium-independent lectin activity. The protein can activate the complement pathway in association with MASPs and sMAP, thereby aiding in host defense through the activation of the lectin pathway. Alternative splicing occurs at this locus and two variants, each encoding a distinct isoform, have been identified.

Alternative names and synonyms associated with FCN3

  • ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen) (FCN3) Antikörper
  • FCNH Antikörper
  • HAKA1 Antikörper

Bezeichner auf Proteinebene für FCN3

H-ficolin , collagen/fibrinogen domain-containing lectin 3 p35 , collagen/fibrinogen domain-containing protein 3 , ficolin 3 , ficolin-3

8547 Homo sapiens
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