Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Wählen Sie die gewünschte Spezies
Anti-HLA class I (zeige MICA Proteine) and class II C3d-binding donor-specific antibodies carried a twofold and 1.5-fold increased risk of kidney graft loss, respectively.
Here we have shown for the first time, that ligand- or insulin (zeige INS Proteine)-mediated activation of PPARgamma (zeige PPARG Proteine) in human hepatoma cell line HepG2 causes the downregulation of C3 gene expression and protein secretion
Single Nucleotide Polymorphism rs11569514 in C3 and haplotypes of C3 variants were associated with schizophrenia in a Han Chinese population.
C3F (zeige LPCAT3 Proteine) polymorphism is associated with viral infections and protection from rejection after liver transplantation.
Pra1 (zeige RABAC1 Proteine) targets C3 by cleaving C3 at a unique site. This inhibited effector function of the activation fragments. The newly formed C3a-like peptide lacked the C-terminal arginine residue needed for C3a-receptor binding and activation. Pra1 (zeige RABAC1 Proteine) also bound to C3a and C3b generated by human convertases and blocked their effector functions, C3a binding to human C3a receptor, C3 antifungal activity, and C3b deposition.
data provide the first evidence that T17M rhodopsin (zeige RHO Proteine) mutant disrupts C3 secretion via the induction of ROS (zeige ROS1 Proteine) and the suppression of TWIST1 (zeige TWIST1 Proteine).
The complement activation factors Bb, C3a, C5a, and MAC were increased significantly in early-onset severe pre-eclampsia (EOSPE) (all P<.01) and late-onset severe pre-eclampsia (LOSPE). (P value: .027, <.001, .001, and <.001, respectively) compared with E/L-control. C1q and C4d were increased significantly in LOSPE (P value: .003 and .014, respectively) compared with L-control.
This study enclosed strong synergistic association of risk genotypes of C3 and CFH (zeige CFH Proteine) Y402H with AMD (zeige AMD1 Proteine). We also revealed synergistic influence of CCL2 (zeige CCL2 Proteine)-2518 and the at-risk genotype of the C3 in AMD (zeige AMD1 Proteine) with an estimated AP = 50.9% (adjusted AP = 24.7%). Present findings show that CCL2 (zeige CCL2 Proteine)-2518 polymorphism is not an innocent bystander (zeige SEPT1 Proteine) in AMD (zeige AMD1 Proteine) susceptibility when combined with the at-risk genotype of C3 (R102G).
Our study shows C3 to be a relatively strong susceptibility gene for advanced-type-AMD (zeige AMD1 Proteine) (exudative-and-geographic-atrophy) in an Iranian population.
BBB disruption is present in ACS (zeige PLA2G15 Proteine), and elevated levels of IL-6 (zeige IL6 Proteine) and C3 in CSF (zeige CSF2 Proteine) in diffuse NPSLE
It has been shown that key proteins in the lectin arm of this pathway, MASP1 (zeige MASP1 Proteine), MASP2 (zeige MASP2 Proteine) and C3, are expressed in the developing cortex and that neuronal migration is impaired in knockout and knockdown mice.
Complement C3 role in the lung cancer progression.
Data report C3 as a novel myogenic factor (zeige MYOG Proteine) secreted by undifferentiated preadipocyte that enhances myogenic differentiation of fetal progenitor cells and adult cells. The results show that complement C3 molecule internalizes myogenic and adipogenic precursor cells and then promotes their differentiation.
C3 deficiency can prolong MHC-II molecule mismatched skin allograft survival.
These findings suggest that C3 protects from early glaucomatous damage, a process that may involve EGFR (zeige EGFR Proteine) signaling and other immune responses in the optic nerve head.
complement C3 or downstream complement activation fragments may play an important role in Abeta (zeige APP Proteine) plaque pathology.
C5 and C5aR (zeige C5AR1 Proteine) have critical roles in the development of C3 glomerulopathy.
Data show that months after irradiation (IR) complement component 3 (C3-/-) mice made fewer errors than WT mice in a reversal learning test indicating better learning capacity in C3-/- mice after IR.
Time-lapse video microscopy established the localization of the complement anaphylatoxin C3a and its receptor on enteric neural crest cells during their migration in the embryonic gut (zeige GUSB Proteine). C3a plays a role in regulating collective and directional cell migration, and in ganglia network organization during enteric nervous system ontogenesis. It regulates cell migration in a N-cadherin (zeige CDH2 Proteine)-dependent process.
Retinal C3 was expressed by microglia/macrophages located in the outer retina in AMD (zeige AMD1 Proteine) eyes. In rodent photo-oxidative damage, C3-expressing microglia/macrophages and complement activation were located in regions of lesion expansion in the outer retina over 2 months
Neural crest cells are coattracted via the complement fragment C3a and its receptor C3aR (zeige C3AR1 Proteine), revealing an unexpected role of complement proteins in early vertebrate development.
Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
, C3a anaphylatoxin
, acylation-stimulating protein cleavage product
, complement C3
, complement component C3
, complement component C3a
, complement component C3b
, acylation stimulating protein
, complement component 3d
, complement factor 3
, complement component 3
, complement C3 alpha chain
, complement component C3d