C3 Proteine (C3)

Bezeichnung:
Complement Component 3 Proteine (C3)
Auf www.antikoerper-online.de finden Sie aktuell 44 Complement Component 3 (C3) Proteine von 8 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen C3 Antikörper (411) und C3 Kits (123) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 582 C3 Produkte verfügbar.
Synonyme:
AHUS5, AI255234, ARMD9, ASP, c3, C3-1, C3a, C3b, C3d, c3_D, CPAMD1, HSE-MSF, Plp, sb:cb26, si:dkey-76b14.4, wu:fi34b03, wu:fj86e11

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Weitere Proteine zu C3 Interaktionspartnern

Zebrafish Complement Component 3 (C3) Interaktionspartner

  1. Neural crest cells are coattracted via the complement fragment C3a and its receptor C3aR (zeige C3AR1 Proteine), revealing an unexpected role of complement proteins in early vertebrate development.

Mouse (Murine) Complement Component 3 (C3) Interaktionspartner

  1. Time-lapse video microscopy established the localization of the complement anaphylatoxin C3a and its receptor on enteric neural crest cells during their migration in the embryonic gut (zeige GUSB Proteine). C3a plays a role in regulating collective and directional cell migration, and in ganglia network organization during enteric nervous system ontogenesis. It regulates cell migration in a N-cadherin (zeige CDH2 Proteine)-dependent process.

  2. Retinal C3 was expressed by microglia/macrophages located in the outer retina in AMD (zeige AMD1 Proteine) eyes. In rodent photo-oxidative damage, C3-expressing microglia/macrophages and complement activation were located in regions of lesion expansion in the outer retina over 2 months

  3. Demonstrate local synthesis of complement proteins by both PDGFRbeta-positive pericytes and CD45 (zeige PTPRC Proteine)-positive cells in kidney fibrosis.

  4. Wild-type C57BL/6 mice with pristane-induced lupus developed a strong IFN signature, which was absent in immunoglobulin-deficient (muMT), C3(-/-) , and CD18 (zeige ITGB2 Proteine)(-/-) mice. In vivo phagocytosis of dead cells was impaired in C3-deficient mice.

  5. Study found that cancer-cell-derived C3 activates the C3a receptor in the choroid plexus epithelium to disrupt the blood-cerebrospinal fluid (CSF (zeige CSF2 Proteine)) barrier. This effect allows plasma components, including amphiregulin (zeige AREG Proteine), and other mitogens to enter the CSF (zeige CSF2 Proteine) and promote cancer cell growth.

  6. We induced anti-myeloperoxidase (zeige MPO Proteine) vasculitis in mice and confirmed a role for complement activation by demonstrating protection in C3-deficient mice.

  7. These data indicated that alpha7-nAChR (zeige CHRNA7 Proteine) caused the inhibition of ASPinduced activation of p38 (zeige CRK Proteine) kinase and NFkappa B to inhibit the production of MCP1 (zeige CCL2 Proteine) and keratinocytederived chemokine (zeige CCL1 Proteine).

  8. This study provideed the evidence that C3a plays a critical role in cerebral endothelial activation and leukocyte recruitment during inflammation in the brain.

  9. Demonstrate that cardiac Sirt1 (zeige SIRT1 Proteine) plays an essential role in caloritc restriction-induced cardioprotection against myocardial I/R injury by suppressing cardiac C3 expression.

  10. The roles of C3, CfB (zeige CFB Proteine), and C3a receptor in the severity of S. aureus induced septic arthritis are reported.

Human Complement Component 3 (C3) Interaktionspartner

  1. THP (zeige UMOD Proteine) appears to participate directly in complement inactivation by its ability to act as a cofactor for C3b degradation.

  2. Decreased C5a expression is associated with increased inflammation in cystic fibrosis (zeige S100A8 Proteine).

  3. C3d-positive glomerular staining is an independent risk factor for the development of end-stage renal disease in ANCA-associated renal vasculitis.

  4. Factor I binds C3b-Factor H (zeige CFH Proteine) between Factor H (zeige CFH Proteine) domains 2 and 3 and a reoriented C3b C-terminal domain and docks onto the first scissile bond, while stabilizing its catalytic domain for proteolytic activity.

  5. The VEGF (zeige VEGFA Proteine) haplotype TGA (zeige TBX1 Proteine) could be used as a marker for poor visual prognosis in Tunisian patients with neovascular AMD (zeige AMD1 Proteine) treated with bevacizumab.

  6. The uromodulin (zeige UMOD Proteine)-CFH (zeige CFH Proteine) interaction enhanced the cofactor activity of CFH (zeige CFH Proteine) for factor I-mediated cleavage of C3b to inactivated C3b.

  7. Generated monoclonal antibody that can only bind to C3d when it manifests itself as the final end product of cleaved C3.

  8. C3 was strongly associated with insulin (zeige INS Proteine) sensitivity after bariatric surgery.

  9. human neutrophil peptides 1-3 and complement activation fragments iC3b were higher in patients with acute thrombotic thrombocytopenic purpura - indicating a role of innate immunity in acute autoimmune TTP (zeige ADAMTS13 Proteine).

  10. CFH (zeige CFH Proteine), ARMS2 (zeige ARMS2 Proteine), and C3 were associated with specific features of neovascularization at the time patients were enrolled in Comparison of Age-Related Macular Degeneration Treatments Trials .

Cow (Bovine) Complement Component 3 (C3) Interaktionspartner

Xenopus laevis Complement Component 3 (C3) Interaktionspartner

  1. Neural crest cells are coattracted via the complement fragment C3a and its receptor C3aR (zeige C3AR1 Proteine), revealing an unexpected role of complement proteins in early vertebrate development.

C3 Protein Überblick

Protein Überblick

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection.

Alternative names and synonyms associated with C3

  • complement component c3a (c3a)
  • complement component 3 (C3)
  • complement component 3 (c3)
  • complement C3-like (LOC100060539)
  • complement component C3 (c3-1)
  • endogenous retrovirus group K, member 13 (ERVK-13)
  • AHUS5 Protein
  • AI255234 Protein
  • ARMD9 Protein
  • ASP Protein
  • c3 Protein
  • C3-1 Protein
  • C3a Protein
  • C3b Protein
  • C3d Protein
  • c3_D Protein
  • CPAMD1 Protein
  • HSE-MSF Protein
  • Plp Protein
  • sb:cb26 Protein
  • si:dkey-76b14.4 Protein
  • wu:fi34b03 Protein
  • wu:fj86e11 Protein

Bezeichner auf Proteinebene für Complement Component 3 Proteine (C3)

cb26 , complement component 3 , acylation stimulating protein , complement C3 , complement component 3d , complement factor 3 , C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 , C3a anaphylatoxin , acylation-stimulating protein cleavage product , complement component C3 , complement component C3a , complement component C3b , prepro-C3 , complement C3 alpha chain , complement component C3d

GENE ID SPEZIES
321046 Danio rerio
455644 Pan troglodytes
703613 Macaca mulatta
100216255 Xenopus (Silurana) tropicalis
100060539 Equus caballus
12266 Mus musculus
100135462 Cavia porcellus
718 Homo sapiens
24232 Rattus norvegicus
397072 Sus scrofa
280677 Bos taurus
100009121 Oryctolagus cuniculus
476728 Canis lupus familiaris
396370 Gallus gallus
443475 Ovis aries
398666 Xenopus laevis
100136951 Oncorhynchus mykiss
100861467 Homo sapiens
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