HEV Ab ELISA Kit

Produktnummer ABIN997026

Produktdetails HEV Ab ELISA Kit

Target: HEV Ab (Hepatitis E Virus Antibody (HEV Ab))

Reaktivität: Hepatitis E Virus (HEV)

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Verwendungszweck: ELISA KIT FOR TOTAL ANTIBODIES TO HEPATITIS E VIRUS Two-Step Incubation, Double Antigen Sandwich Principle

Proben: Serum

Analytische Methode: Qualitative

Spezifität: 99.60%

Sensitivität: 99.80%

Anwendungsinformationen

Probenmenge: 50 μL

Testdauer: 1 - 2 h

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C

Haltbarkeit: 12-18 months

Details zu HEV Ab

Target: HEV Ab (Hepatitis E Virus Antibody (HEV Ab))

Andere Bezeichnung: HEV Ab (HEV Ab Produkte)

Hintergrund: Hepatitis E virus (HEV) is a non-enveloped, single- stranded RNA virus identified in 1990. Infection with HEV induces acute or sub-clinical liver diseases similar to hepatitis A. HEV infections, endemic and frequently epidemic in developing countries, is seen also in developed countries in a sporadic form with or without a history of traveling to endemic area. The overall case-fatality is 0.5~3%, and much higher (15~25%) among pregnant women. A hypothesis that HEV infection is a zoonosis was presented in 1995. Then a swine HEV and later an avian HEV were identified and sequenced separately in 1997 and 2001. Since then, HEV infection include anti-HEV, viremia and feces excretion of HEV was seen in a wide variety of animals, i.e., swine, rodents, wild monkeys, deer, cow, goats, dogs and chicken in both the developing and developed countries. A direct testimony was reported that the consumption of uncooked dear meat contaminated with HEV led to acute hepatitis E in human, and HEV genome sequences can be detected in pork livers available in the supermarkets in Japan. With the discovery of conformational epitopes in HEV, HEV serology was further explored and understood. The phenomenon of long-lasting and protective antibodies to HEV was observed which greatly enhance the understanding to the diagnosis, epidemiology, zoonosis-related studies and vaccine development.