The kit has been especially developed for the quantitative analysis anti-PD-1 antibody in human serum samples based on the principle of competing.
Proben
Serum
Analytische Methode
Quantitative
Spezifität
This kit has been tested for multiple investigational PD-1 antibodies, as well as the commercially available Keytruda® and Opdivo®. There is no requirement for the species and subtype of the antibody.
Bestandteile
Human PD-1 Biotinylated anti-PD-1 antibody Streptavidin-HRP Anti-PD-1 antibody
1. Coat the plate with human PD-1 2. Add the mixture of your sample and biotinylated anti-PD-1 antibody 3. Add Streptavidin-HRP followed by TMB or other colorimetric HRP substrate 4. Record the OD readings and analyze the serum concentration.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Lagerung
-20 °C
Informationen zur Lagerung
No activity loss was observed after storage at: -20°C for 1 year in lyophilized state after receipt, -80°C for 4 months under sterile conditions after reconstitution with carrier protein., Powder,RT
Target
Anti-PD-1 Ab
Hintergrund
How a therapeutic antibody is metabolized in the body is pertinently relevant to its efficacy. Therefore, pharmacokinetics study is an important part of the drug development.PD-1 is probably the most targeted molecule in today's pharmaceutical industry, t