PON1 ELISA Kit

Produktnummer ABIN5510758

Dieses Colorimetric ELISA-Kit wurde entwickelt für die quantitative Messung von Maus PON1.

Kurzübersicht für PON1 ELISA Kit (ABIN5510758)

Target: PON1 (Paraoxonase 1 (PON1))

Bindungsspezifität: AA 30-355

Reaktivität: Maus

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails PON1 ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse PON1

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: E.Coli, Immunogen sequence: A30-L355

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Produktmerkmale:

Tissue Specificity: Plasma, liver, kidney, heart, brain, small intestine and lung. In the plasma, associated with HDL.

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu PON1

Target: PON1 (Paraoxonase 1 (PON1))

Andere Bezeichnung: Pon1

Hintergrund:

Protein Function: Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification.

Background: Serum paraoxonase/arylesterase 1 (PON1) also known as aromatic esterase 1 or serum aryldialkylphosphatase 1 is an enzyme that in humans is encoded by the PON1 gene. The PON gene was mapped to chromosome 7q21-q22, and the mouse Pon1 gene was mapped to the proximal end of chromosome 6. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL).

Synonyms: Serum paraoxonase/arylesterase 1, PON 1, 3.1.1.2

Full Gene Name: paraoxonase 1

Cellular Localisation: Secreted, extracellular space.

UniProt: P52430