GDF2 ELISA Kit

Produktnummer ABIN5510718

Human GDF2 ELISA-Kit Colorimetric-Assay zur Quantifizierung von Human GDF2.

Kurzübersicht für GDF2 ELISA Kit (ABIN5510718)

Target: GDF2 (Growth Differentiation Factor 2 (GDF2))

Bindungsspezifität: AA 320-429

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails GDF2 ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human BMP-9

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: CHO, Immunogen sequence: S320-R429

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu GDF2

Target: GDF2 (Growth Differentiation Factor 2 (GDF2))

Andere Bezeichnung: GDF2

Hintergrund:

Protein Function: Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.

Background: Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Homozygous null mice exhibit malformations of the vasculature and skeleton.

Synonyms: Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9, GDF2, BMP9,

Full Gene Name: growth differentiation factor 2

Cellular Localisation: Secreted

UniProt: Q9UK05

Pathways: Transition Metal Ion Homeostasis