GREM2 ELISA Kit

Produktnummer ABIN5510700

Kaninchen GREM2 ELISA-Kit Colorimetric-Assay zur Quantifizierung von Kaninchen GREM2.

Kurzübersicht für GREM2 ELISA Kit (ABIN5510700)

Target: GREM2 (Gremlin 2 (GREM2))

Bindungsspezifität: AA 22-168

Reaktivität: Kaninchen

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails GREM2 ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of rabbit GREM2

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: E.coli
Immunogen sequence: R22-Q168

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu GREM2

Target: GREM2 (Gremlin 2 (GREM2))

Andere Bezeichnung: GREM2

Hintergrund:

Protein Function: Cytokine that inhibits the activity of BMP2 and BMP4 in a dose-dependent manner, and thereby modulates signaling by BMP family members. Contributes to the regulation of embryonic morphogenesis via BMP family members. Antagonizes BMP4-induced suppression of progesterone production in granulosa cells (By similarity). .

Background: GREM2, also known as PRDC, is one of several BMP antagonists that regulate the functions of BMPs during embryonic development and tissue differentiation. BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. The PRDC gene is mapped to chromosome 1q43.

Synonyms: Gremlin-2,Cysteine knot superfamily 1, BMP antagonist 2,DAN domain family member 3,Protein related to DAN and cerberus,GREM2,CKTSF1B2, DAND3, PRDC,

Full Gene Name: Gremlin-2

Cellular Localisation: Secreted.

UniProt: Q9H772