PRSS3 ELISA Kit

Produktnummer ABIN5510696

Dieses Human PRSS3 ELISA-Kit ist ein Colorimetric ELISA-Kit, das dafür entwickelt wurde, Human PRSS3 zu quantifizieren.

Kurzübersicht für PRSS3 ELISA Kit (ABIN5510696)

Target: PRSS3 (Protease, serine, 3 (PRSS3))

Bindungsspezifität: AA 16-247

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails PRSS3 ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Pan Trypsin

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: NSO
Immunogen sequence: A16-S247

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Produktmerkmale:

Tissue Specificity: Expressed in pancreas and brain. Also expressed in Paneth cells, at the base of small intestinal crypts. .

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu PRSS3

Target: PRSS3 (Protease, serine, 3 (PRSS3))

Andere Bezeichnung: PRSS3

Hintergrund:

Protein Function: Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5. .

Background: Trypsin is a serine protease from the PA clan superfamily, found in the digestive system of many vertebrates, where it hydrolyses proteins. In the duodenum, trypsin catalyzes the hydrolysis of peptide bonds, breaking down proteins into smaller peptides. The peptide products are then further hydrolyzed into amino acids via other proteases, rendering them available for absorption into the blood stream. Tryptic digestion is a necessary step in protein absorption as proteins are generally too large to be absorbed through the lining of the small intestine. Additionally, Trypsin is produced as the inactive zymogen trypsinogen in the pancreas. When the pancreas is stimulated by cholecystokinin, it is then secreted into the first part of the small intestine (the duodenum) via the pancreatic duct. Once in the small intestine, the enzyme enteropeptidase activates trypsinogen into trypsin by proteolytic cleavage. Auto catalysis can happen with trypsin using trypsinogen as the substrate. This activation mechanism is common for most serine proteases, and serves to prevent autodegradation of the pancreas.

Synonyms: Trypsin-3,3.4.21.4,Brain trypsinogen,Mesotrypsinogen,Serine protease 3,Serine protease 4,Trypsin III,Trypsin IV,PRSS3,PRSS4, TRY3, TRY4,

Full Gene Name: Trypsin-3

Cellular Localisation: Secreted.

UniProt: P35030