Peroxiredoxin 2 ELISA Kit

Produktnummer ABIN5510694

Human Peroxiredoxin 2 ELISA-Kit Colorimetric-Assay zur Quantifizierung von Human Peroxiredoxin 2.

Kurzübersicht für Peroxiredoxin 2 ELISA Kit (ABIN5510694)

Target: Peroxiredoxin 2 (PRDX2)

Bindungsspezifität: AA 2-198

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails Peroxiredoxin 2 ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Peroxiredoxin 2

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: NSO, Immunogen sequence: A2-N198

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu Peroxiredoxin 2

Target: Peroxiredoxin 2 (PRDX2)

Andere Bezeichnung: PRDX2

Hintergrund:

Protein Function: Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).

Background: Peroxiredoxin-2 is a protein that in humans is encoded by the PRDX2 gene. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. It may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.

Synonyms: Peroxiredoxin-2,1.11.1.15,Natural killer cell-enhancing factor B,NKEF-B,PRP,Thiol-specific antioxidant protein,TSA,Thioredoxin peroxidase 1,Thioredoxin-dependent peroxide reductase 1,PRDX2,NKEFB, TDPX1,

Full Gene Name: Peroxiredoxin-2

Cellular Localisation: Cytoplasm.

UniProt: P32119