TREML1 ELISA Kit

Produktnummer ABIN5510688

Human TREML1 ELISA-Kit Colorimetric-Assay zur Quantifizierung von Human TREML1 in

Kurzübersicht für TREML1 ELISA Kit (ABIN5510688)

Target: TREML1 (Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1))

Bindungsspezifität: AA 16-162

Reaktivität: Human

Nachweismethode: Colorimetric

Methodentyp: Sandwich ELISA

Applikation: ELISA

Produktdetails TREML1 ELISA Kit

Verwendungszweck: Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human TREML1

Marke: PicoKine™

Analytische Methode: Quantitative

Spezifität: Expression system for standard: NSO
Immunogen sequence: Q16-P162

Kreuzreaktivität (Details): There is no detectable cross-reactivity with other relevant proteins.

Produktmerkmale:

Tissue Specificity: Detected in platelets, monocytic leukemia and in T-cell leukemia. .

Anwendungsinformationen

Plattentyp: Pre-coated

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Haltbarkeit: 12 months

Details zu TREML1

Target: TREML1 (Triggering Receptor Expressed On Myeloid Cells-Like 1 (TREML1))

Andere Bezeichnung: TREML1

Hintergrund:

Protein Function: Cell surface receptor that may play a role in the innate and adaptive immune response. .

Background: Trem-like transcript 1 protein is a protein that in humans is encoded by the TREML1 gene. This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. This protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants.

Synonyms: Trem-like transcript 1 protein,TLT-1,Triggering receptor expressed on myeloid cells-like protein 1,TREML1,TLT1,UNQ1825/PRO3438,

Full Gene Name: Trem-like transcript 1 protein

Cellular Localisation: Cell membrane, Single-pass type I membrane protein . Cytoplasm . Sequestered in cytoplasmic vesicles in resting platelets (PubMed:15100151). Transported to the cell surface after stimulation by thrombin (PubMed:15100151). Soluble fragments can be released into the serum by proteolysis (PubMed:16505478).

UniProt: Q86YW5